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2423679

Project Grant

Overview

Grant Description
SBIR Phase I: Development of 18F-radiotracer kits for detection of biomarkers by positron emission tomography.

The broader impact and commercial potential of this Small Business Innovation Research (SBIR) Phase I project extend to several key areas.

Firstly, it aims to enhance the quality of healthcare and improve the health outcomes of the American public by offering cutting-edge diagnostic tools for the detection and assessment of various diseases.

These advanced diagnostics will provide clinicians with precise and reliable information, thereby improving disease management and patient care.

Secondly, the project will create valuable opportunities to train a skilled STEM workforce in the United States.

By hiring individuals with expertise in chemistry and biology, it will contribute to the advancement of scientific frontiers and support participation in the technology-driven economy.

Thirdly, the project fosters the integration of research through collaboration between industry and academia.

By leveraging the expertise of non-profit research institutions, it will expand the practical applications of scientific discoveries to industry settings.

Lastly, the development of a globally demanded product is expected to enhance the economic competitiveness of the United States on the international stage.

This Small Business Innovation Research (SBIR) Phase I project focuses on harnessing recent advancements in the basic sciences, particularly in chemistry and biology, to design innovative diagnostic products.

These products have applications in both preclinical research and clinical diagnostics, particularly in the field of disease detection and treatment.

The proposed diagnostic agents, designed for use with positron emission tomography (PET), will assist researchers and physicians specializing in oncology.

These tools will enable more precise selection of appropriate therapies for cancer patients, providing critical data on the early assessment of immunotherapy, which is considered a breakthrough treatment in oncology.

The project not only advances scientific knowledge and techniques but also addresses technical challenges in developing novel PET diagnostic agents.

A multidisciplinary team, renowned for their expertise in nuclear chemistry, medical imaging, and immunology, is collaborating to ensure the successful completion of the project's objectives.

Their combined efforts will propel the development of these innovative products and technologies, ultimately facilitating their use in human healthcare.

This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the foundation's intellectual merit and broader impacts review criteria.

Subawards are planned for this award.
Funding Goals
THE GOAL OF THIS FUNDING OPPORTUNITY, "NSF SMALL BUSINESS INNOVATION RESEARCH (SBIR)/ SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAMS PHASE I", IS IDENTIFIED IN THE LINK: HTTPS://WWW.NSF.GOV/PUBLICATIONS/PUB_SUMM.JSP?ODS_KEY=NSF23515
Awarding / Funding Agency
Place of Performance
Tucson, Arizona 85741-3691 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the total obligations have increased 7% from $275,000 to $295,000.
Theracea Pharma Lc was awarded Project Grant 2423679 worth $295,000 from National Science Foundation in September 2024 with work to be completed primarily in Tucson Arizona United States. The grant has a duration of 1 year and was awarded through assistance program 47.084 NSF Technology, Innovation, and Partnerships. The Project Grant was awarded through grant opportunity NSF Small Business Innovation Research / Small Business Technology Transfer Phase I Programs.

SBIR Details

Research Type
SBIR Phase I
Title
SBIR Phase I: Development of 18F-radiotracer kits for detection of biomarkers by Positron Emission Tomography
Abstract
The broader impact and commercial potential of this Small Business Innovation Research (SBIR) Phase I project extend to several key areas. Firstly, it aims to enhance the quality of healthcare and improve the health outcomes of the American public by offering cutting-edge diagnostic tools for the detection and assessment of various diseases. These advanced diagnostics will provide clinicians with precise and reliable information, thereby improving disease management and patient care. Secondly, the project will create valuable opportunities to train a skilled STEM workforce in the United States. By hiring individuals with expertise in chemistry and biology, it will contribute to the advancement of scientific frontiers and support participation in the technology-driven economy. Thirdly, the project fosters the integration of research through collaboration between industry and academia. By leveraging the expertise of non-profit research institutions, it will expand the practical applications of scientific discoveries to industry settings. Lastly, the development of a globally demanded product is expected to enhance the economic competitiveness of the United States on the international stage. This Small Business Innovation Research SBIR Phase I project focuses on harnessing recent advancements in the basic sciences, particularly in chemistry and biology, to design innovative diagnostic products. These products have applications in both preclinical research and clinical diagnostics, particularly in the field of disease detection and treatment. The proposed diagnostic agents, designed for use with Positron Emission Tomography (PET), will assist researchers and physicians specializing in oncology. These tools will enable more precise selection of appropriate therapies for cancer patients, providing critical data on the early assessment of immunotherapy, which is considered a breakthrough treatment in oncology. The project not only advances scientific knowledge and techniques but also addresses technical challenges in developing novel PET diagnostic agents. A multidisciplinary team, renowned for their expertise in nuclear chemistry, medical imaging, and immunology, is collaborating to ensure the successful completion of the project’s objectives. Their combined efforts will propel the development of these innovative products and technologies, ultimately facilitating their use in human healthcare. This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Topic Code
BM
Solicitation Number
NSF 23-515

Status
(Ongoing)

Last Modified 4/4/25

Period of Performance
9/1/24
Start Date
8/31/25
End Date
98.0% Complete

Funding Split
$295.0K
Federal Obligation
$0.0
Non-Federal Obligation
$295.0K
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to 2423679

Transaction History

Modifications to 2423679

Additional Detail

Award ID FAIN
2423679
SAI Number
None
Award ID URI
SAI EXEMPT
Awardee Classifications
Small Business
Awarding Office
491503 TRANSLATIONAL IMPACTS
Funding Office
491503 TRANSLATIONAL IMPACTS
Awardee UEI
KSNLTEALRQL5
Awardee CAGE
89EB8
Performance District
AZ-06
Senators
Kyrsten Sinema
Mark Kelly
Modified: 4/4/25