2423454
Project Grant
Overview
Grant Description
SBIR Phase I: Neurobionics Omnifiber: A multifunctional neural probe for advancing neuroscience research.
The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to enable novel preclinical research into brain disorders and screening of neurological drug candidates by providing a versatile, multifunctional tool for neuroscience research.
This flexible, fiber-based neural probe integrates electrical, optical, and chemical capabilities into a single implantable device for the brain, empowering scientists to combine recording of neural activity with electrical and optical stimulation along with targeted delivery of pharmacological agents in animal models.
This is a crucial advance to enable insights into neurological disorders and translation of neuroscience discoveries into effective therapies.
The technology has significant commercial potential in the neuroscience research market ($240M annually) as well as the pharmaceutical market for screening of neurological drug candidates ($600M annually) based on both primary and secondary market research.
The completion of this Phase I project will significantly de-risk the commercialization of this groundbreaking neurotechnology.
This Small Business Innovation Research (SBIR) Phase I project will address a key shortcoming of today’s neural interfacing research technologies: a lack of available tools that can combine key methods spanning electrical, optical, and chemical modalities into a single device in a single brain region.
To address this challenge, a novel neural probe will be developed based on multi-material, flexible, microscopic, bioelectronic fiber technology that integrates diverse capabilities including electrophysiological recording, optical and electrical stimulation, drug delivery, and neurotransmitter monitoring.
In this Phase I project, key technical challenges to commercializing and scaling the multifunctional neural probe’s production will be addressed by (1) integrating electrodes and microfluidic channels along the length of the probe to achieve broader spatial sampling, (2) developing a novel integrated back-end connector comprising electrical pins, optical ferrules, and fluidic fittings, and (3) establishing an automated and scalable manufacturing approach.
At the conclusion of the project, a versatile tool enabling novel neuroscience research paradigms will be ready for commercialization.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the foundation's intellectual merit and broader impacts review criteria.
Subawards are not planned for this award.
The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to enable novel preclinical research into brain disorders and screening of neurological drug candidates by providing a versatile, multifunctional tool for neuroscience research.
This flexible, fiber-based neural probe integrates electrical, optical, and chemical capabilities into a single implantable device for the brain, empowering scientists to combine recording of neural activity with electrical and optical stimulation along with targeted delivery of pharmacological agents in animal models.
This is a crucial advance to enable insights into neurological disorders and translation of neuroscience discoveries into effective therapies.
The technology has significant commercial potential in the neuroscience research market ($240M annually) as well as the pharmaceutical market for screening of neurological drug candidates ($600M annually) based on both primary and secondary market research.
The completion of this Phase I project will significantly de-risk the commercialization of this groundbreaking neurotechnology.
This Small Business Innovation Research (SBIR) Phase I project will address a key shortcoming of today’s neural interfacing research technologies: a lack of available tools that can combine key methods spanning electrical, optical, and chemical modalities into a single device in a single brain region.
To address this challenge, a novel neural probe will be developed based on multi-material, flexible, microscopic, bioelectronic fiber technology that integrates diverse capabilities including electrophysiological recording, optical and electrical stimulation, drug delivery, and neurotransmitter monitoring.
In this Phase I project, key technical challenges to commercializing and scaling the multifunctional neural probe’s production will be addressed by (1) integrating electrodes and microfluidic channels along the length of the probe to achieve broader spatial sampling, (2) developing a novel integrated back-end connector comprising electrical pins, optical ferrules, and fluidic fittings, and (3) establishing an automated and scalable manufacturing approach.
At the conclusion of the project, a versatile tool enabling novel neuroscience research paradigms will be ready for commercialization.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the foundation's intellectual merit and broader impacts review criteria.
Subawards are not planned for this award.
Awardee
Funding Goals
THE GOAL OF THIS FUNDING OPPORTUNITY, "NSF SMALL BUSINESS INNOVATION RESEARCH (SBIR)/ SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAMS PHASE I", IS IDENTIFIED IN THE LINK: HTTPS://WWW.NSF.GOV/PUBLICATIONS/PUB_SUMM.JSP?ODS_KEY=NSF23515
Grant Program (CFDA)
Awarding / Funding Agency
Place of Performance
Somerville,
Massachusetts
02143-2267
United States
Geographic Scope
Single Zip Code
Neurobionics was awarded
Project Grant 2423454
worth $254,456
from National Science Foundation in August 2024 with work to be completed primarily in Somerville Massachusetts United States.
The grant
has a duration of 5 months and
was awarded through assistance program 47.084 NSF Technology, Innovation, and Partnerships.
The Project Grant was awarded through grant opportunity NSF Small Business Innovation Research / Small Business Technology Transfer Phase I Programs.
SBIR Details
Research Type
SBIR Phase I
Title
SBIR Phase I: NeuroBionics OmniFiber: A Multifunctional Neural Probe for Advancing Neuroscience Research
Abstract
The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to enable novel preclinical research into brain disorders and screening of neurological drug candidates by providing a versatile, multifunctional tool for neuroscience research. This flexible, fiber-based neural probe integrates electrical, optical, and chemical capabilities into a single implantable device for the brain, empowering scientists to combine recording of neural activity with electrical and optical stimulation along with targeted delivery of pharmacological agents in animal models. This is a crucial advance to enable insights into neurological disorders and translation of neuroscience discoveries into effective therapies. The technology has significant commercial potential in the neuroscience research market ($240M Annually) as well as the pharmaceutical market for screening of neurological drug candidates ($600M Annually) based on both primary and secondary market research. The completion of this Phase I project will significantly de-risk the commercialization of this groundbreaking neurotechnology.
This Small Business Innovation Research (SBIR) Phase I project will address a key shortcoming of today’s neural interfacing research technologies: a lack of available tools that can combine key methods spanning electrical, optical, and chemical modalities into a single device in a single brain region. To address this challenge, a novel neural probe will be developed based on multi-material, flexible, microscopic, bioelectronic fiber technology that integrates diverse capabilities including electrophysiological recording, optical and electrical stimulation, drug delivery, and neurotransmitter monitoring. In this Phase I project, key technical challenges to commercializing and scaling the multifunctional neural probe’s production will be addressed by (1) integrating electrodes and microfluidic channels along the length of the probe to achieve broader spatial sampling, (2) developing a novel integrated back-end connector comprising electrical pins, optical ferrules, and fluidic fittings, and (3) establishing an automated and scalable manufacturing approach. At the conclusion of the project, a versatile tool enabling novel neuroscience research paradigms will be ready for commercialization.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Topic Code
BM
Solicitation Number
NSF 23-515
Status
(Complete)
Last Modified 8/27/24
Period of Performance
8/15/24
Start Date
1/31/25
End Date
Funding Split
$254.5K
Federal Obligation
$0.0
Non-Federal Obligation
$254.5K
Total Obligated
Activity Timeline
Additional Detail
Award ID FAIN
2423454
SAI Number
None
Award ID URI
SAI EXEMPT
Awardee Classifications
Small Business
Awarding Office
491503 TRANSLATIONAL IMPACTS
Funding Office
491503 TRANSLATIONAL IMPACTS
Awardee UEI
UUKGN9CKYMY3
Awardee CAGE
9NG33
Performance District
MA-07
Senators
Edward Markey
Elizabeth Warren
Elizabeth Warren
Modified: 8/27/24