2406646
Project Grant
Overview
Grant Description
SBIR Phase I: Tendon-implant integration in a tendon-mounted implant for reconstructive surgery.
The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is a novel medical device approach for restoring movement and recovery during reconstructive surgery.
The surgically implanted system integrates a differentiated mechanical approach for redirecting internal forces and movement transmission of the tendons and ligaments in order to restore articulation and strength.
The overall objective is to develop an implantable system capable of chronically integrating lateral movement from a tendon-mounted implant and two tendons, to reroute movement from a single tendon to multiple tendons.
If successful, the system will provide greater restorative function to grip strength and rehabilitative compensation of arm movements following reconstructive surgeries due to a variety of neuromuscular conditions including but not limited to spinal cord injury or nerve trauma.
The new implantable approach aims to improve surgical functional outcomes for over 100,000 patients each year through improved manual dexterity and recovery.
This Small Business Innovation Research (SBIR) Phase I project advances the design engineering and preclinical evidence validation for a small implantable medical device with an integrated passive swiveling mechanism using biological tendons.
The first stage will complete design and fabrication of the prototype incorporating biomechanical grooves and pores to facilitate tendon in-growth.
The second stage will validate the design with a chronic lapine study of lateral integration between a tendon-mounted implant and two tendons in order to reroute movement from a single tendon to multiple tendons.
Upon surgical implantation, the device-tendon construct aims to distribute movement from one muscle across multiple output tendons, while allowing each tendon to reach its own tension equilibrium.
A histological and mechanical evaluation will be performed on the tendon-implant attachment to demonstrate chronic feasibility.
It is expected the implant will significantly improve function, integrate with the tendons, and not adversely impact tendon health.
Upon completion, the design and preclinical evidence will be integrated into a product design plan to reach human use during the subsequent stage.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Subawards are not planned for this award.
The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is a novel medical device approach for restoring movement and recovery during reconstructive surgery.
The surgically implanted system integrates a differentiated mechanical approach for redirecting internal forces and movement transmission of the tendons and ligaments in order to restore articulation and strength.
The overall objective is to develop an implantable system capable of chronically integrating lateral movement from a tendon-mounted implant and two tendons, to reroute movement from a single tendon to multiple tendons.
If successful, the system will provide greater restorative function to grip strength and rehabilitative compensation of arm movements following reconstructive surgeries due to a variety of neuromuscular conditions including but not limited to spinal cord injury or nerve trauma.
The new implantable approach aims to improve surgical functional outcomes for over 100,000 patients each year through improved manual dexterity and recovery.
This Small Business Innovation Research (SBIR) Phase I project advances the design engineering and preclinical evidence validation for a small implantable medical device with an integrated passive swiveling mechanism using biological tendons.
The first stage will complete design and fabrication of the prototype incorporating biomechanical grooves and pores to facilitate tendon in-growth.
The second stage will validate the design with a chronic lapine study of lateral integration between a tendon-mounted implant and two tendons in order to reroute movement from a single tendon to multiple tendons.
Upon surgical implantation, the device-tendon construct aims to distribute movement from one muscle across multiple output tendons, while allowing each tendon to reach its own tension equilibrium.
A histological and mechanical evaluation will be performed on the tendon-implant attachment to demonstrate chronic feasibility.
It is expected the implant will significantly improve function, integrate with the tendons, and not adversely impact tendon health.
Upon completion, the design and preclinical evidence will be integrated into a product design plan to reach human use during the subsequent stage.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Subawards are not planned for this award.
Awardee
Funding Goals
THE GOAL OF THIS FUNDING OPPORTUNITY, "NSF SMALL BUSINESS INNOVATION RESEARCH (SBIR)/ SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAMS PHASE I", IS IDENTIFIED IN THE LINK: HTTPS://WWW.NSF.GOV/PUBLICATIONS/PUB_SUMM.JSP?ODS_KEY=NSF23515
Grant Program (CFDA)
Awarding / Funding Agency
Place of Performance
Corvallis,
Oregon
97330-4254
United States
Geographic Scope
Single Zip Code
Orthomechanica was awarded
Project Grant 2406646
worth $275,000
from National Science Foundation in September 2024 with work to be completed primarily in Corvallis Oregon United States.
The grant
has a duration of 1 year and
was awarded through assistance program 47.084 NSF Technology, Innovation, and Partnerships.
The Project Grant was awarded through grant opportunity NSF Small Business Innovation Research / Small Business Technology Transfer Phase I Programs.
SBIR Details
Research Type
SBIR Phase I
Title
SBIR Phase I: Tendon-Implant Integration in a Tendon-Mounted Implant for Reconstructive Surgery
Abstract
The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is a novel medical device approach for restoring movement and recovery during reconstructive surgery. The surgically implanted system integrates a differentiated mechanical approach for redirecting internal forces and movement transmission of the tendons and ligaments in order to restore articulation and strength. The overall objective is to develop an implatable system capable of chronically integrating lateral movement from a tendon-mounted implant and two tendons, to reroute movement from a single tendon to multiple tendons. If successful, the system will provide greater restorative function to grip strength and rehabilitative compensation of arm movements following reconstructive surgeries due to a vatiery of neuromuscular conditions including but not limited to spinal cord injury or nerve trauma. The new implantable approach aims to improve surgical functional outcomes for over 100,000 patients each year through improved manual dexterity and recovery.
This Small Business Innovation Research (SBIR) Phase I project advances the design engineering and preclinical evidence validation for a small implantable medical device with an integrated passive swiveling mechanism using biological tendons. The first stage will complete design and fabrication of the prototype incorporating biomechanical grooves and pores to facilitate tendon in-growth. The second stage will validate the design with a chronic lapine study of lateral integration between a tendon-mounted implant and two tendons in order to reroute movement from a single tendon to multiple tendons. Upon surgical implantation, the device-tendon construct aims to distributes movement from one muscle across multiple output tendons, while allowing each tendon to reach its own tension equilibrium. A histological and mechanical evaluation to will be performed on the tendon-implant attachment to demonstrate chronic feasibility. It is expected the implant will significantly improve function, integrate with the tendons, and not adversely impact tendon health. Upon completion, the design and preclinical evidence will be integrated into a product design plan to reach human use during the subsequent stage.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Topic Code
MD
Solicitation Number
NSF 23-515
Status
(Complete)
Last Modified 9/25/24
Period of Performance
9/15/24
Start Date
8/31/25
End Date
Funding Split
$275.0K
Federal Obligation
$0.0
Non-Federal Obligation
$275.0K
Total Obligated
Activity Timeline
Additional Detail
Award ID FAIN
2406646
SAI Number
None
Award ID URI
SAI EXEMPT
Awardee Classifications
Small Business
Awarding Office
491503 TRANSLATIONAL IMPACTS
Funding Office
491503 TRANSLATIONAL IMPACTS
Awardee UEI
P3E9WB3CDHC5
Awardee CAGE
99BL9
Performance District
OR-04
Senators
Jeff Merkley
Ron Wyden
Ron Wyden
Modified: 9/25/24