2404556
Project Grant
Overview
Grant Description
Sttr Phase I: Hand-held induction heaters for pancreatic and prostatic cancer treatment.
The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is a portable device providing focused magnetic field applications for treating cancer using magnetic nanoparticle-based cancer strategies, but in patients with metallic implants (e.g., joint replacements, pacemakers, stents) who are currently ineligible for the treatment due to their peripheral effects.
Cancer treatments typically require customized strategies and the appropriate tools for treatment without damaging the surrounding tissues.
The proposed innovation aims to provide contactless heating of electrically conductive materials in challenging areas to directly access the patient, enabling access to a subset of patients for an emerging therapy for cancer treatment who are currently ineligible due to compatibility issues with the form of energy delivery and their peripheral effects.
The potential opportunity of the 2 million patients with either pancreatic and prostate cancer who may be contraindicated for existing systems represents a 131MM annual market opportunity.
This Small Business Innovation Research (SBIR) Phase I project aims to advance the development and evaluation of hand-held induction heaters for cancer treatment.
The system aims to provide magnetic fluid hyperthermia (MFH), an emerging electromagnetic thermal treatment for treating cancer.
The system proposes benefits to current larger and more complex systems with exclusion criteria for patients with metallic implants below their neck due to heating risks.
The objectives are to (A) develop methods to deliver significant thermal energy to pancreatic and prostate porcine organs in vivo, and (B) characterize and validate the extent and severity of tissue damage using patented, unique, deep technology on swine models.
This project will focus on its feasibility as a cancer treatment, to advance the proposed technology from a Technology Readiness Level 4, representing laboratory validation, to Level 6 indicating the technology has been validated in a relevant environment.
The Phase 1 results will finalize feasibility assessments for a novel instrument that enables an emerging MFH cancer treatment but for currently contraindicated patients, into clinical practice for human use, at a future stage.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the foundation's intellectual merit and broader impacts review criteria.
Subawards are planned for this award.
The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is a portable device providing focused magnetic field applications for treating cancer using magnetic nanoparticle-based cancer strategies, but in patients with metallic implants (e.g., joint replacements, pacemakers, stents) who are currently ineligible for the treatment due to their peripheral effects.
Cancer treatments typically require customized strategies and the appropriate tools for treatment without damaging the surrounding tissues.
The proposed innovation aims to provide contactless heating of electrically conductive materials in challenging areas to directly access the patient, enabling access to a subset of patients for an emerging therapy for cancer treatment who are currently ineligible due to compatibility issues with the form of energy delivery and their peripheral effects.
The potential opportunity of the 2 million patients with either pancreatic and prostate cancer who may be contraindicated for existing systems represents a 131MM annual market opportunity.
This Small Business Innovation Research (SBIR) Phase I project aims to advance the development and evaluation of hand-held induction heaters for cancer treatment.
The system aims to provide magnetic fluid hyperthermia (MFH), an emerging electromagnetic thermal treatment for treating cancer.
The system proposes benefits to current larger and more complex systems with exclusion criteria for patients with metallic implants below their neck due to heating risks.
The objectives are to (A) develop methods to deliver significant thermal energy to pancreatic and prostate porcine organs in vivo, and (B) characterize and validate the extent and severity of tissue damage using patented, unique, deep technology on swine models.
This project will focus on its feasibility as a cancer treatment, to advance the proposed technology from a Technology Readiness Level 4, representing laboratory validation, to Level 6 indicating the technology has been validated in a relevant environment.
The Phase 1 results will finalize feasibility assessments for a novel instrument that enables an emerging MFH cancer treatment but for currently contraindicated patients, into clinical practice for human use, at a future stage.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the foundation's intellectual merit and broader impacts review criteria.
Subawards are planned for this award.
Awardee
Funding Goals
THE GOAL OF THIS FUNDING OPPORTUNITY, "NSF SMALL BUSINESS INNOVATION RESEARCH (SBIR)/ SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAMS PHASE I", IS IDENTIFIED IN THE LINK: HTTPS://WWW.NSF.GOV/PUBLICATIONS/PUB_SUMM.JSP?ODS_KEY=NSF23515
Grant Program (CFDA)
Awarding / Funding Agency
Place of Performance
Mayaguez,
Puerto Rico
00680
United States
Geographic Scope
Single Zip Code
Ihnnova was awarded
Project Grant 2404556
worth $275,000
from National Science Foundation in October 2024 with work to be completed primarily in Mayaguez Puerto Rico United States.
The grant
has a duration of 1 year and
was awarded through assistance program 47.084 NSF Technology, Innovation, and Partnerships.
The Project Grant was awarded through grant opportunity NSF Small Business Innovation Research / Small Business Technology Transfer Phase I Programs.
SBIR Details
Research Type
STTR Phase I
Title
STTR Phase I: Hand-Held Induction Heaters for Pancreatic and Prostatic Cancer Treatment
Abstract
The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is a portable device providing focused magnetic field applications for treating cancer using magnetic nanoparticle-based cancer strategies, but in patients with metallic implants (e.g., joint replacements, pacemakers, stents) who are currently ineligible for the treatment due to their peripheral effects. Cancer treatments typically require customized strategies and the appropriate tools for treatment without damaging the surrounding tissues. The proposed innovation aims to provide contactless heating of electrically conductive materials in challenging areas to directly access of the patient, enabling access to a subset of patients for an emerging therapy for cancer treatment who are currently ineligible due to compatibility issues with the form of energy delivery and their peripheral effects. The potential opportunity of the 2 million patients with either pancreatic and prostate cancer who may be contraindicated for existing systems represents a 131MM annual market opportunity.
This Small Business Innovation Research (SBIR) Phase I project aims to advance the development and evaluation of hand-held induction heaters for cancer treatment. The system aims to provide magnetic fluid hyperthermia (MFH), an emerging electromagnetic thermal treatment for treating cancer. The system proposes benefits to current larger and more complex systems with exclusion criteria for patients with metallic implants below their neck due to heating risks. The objectives are to (a) develop methods to deliver significant thermal energy to pancreatic and prostate porcine organs in vivo, and (b) characterize and validate the extent and severity of tissue damage using patented, unique, deep technology on swine models. This project will focus on its feasibility as a cancer treatment, to advance the proposed technology from a Technology Readiness Level 4, representing laboratory validation, to Level 6 indicating the technology has been validated in a relevant environment. The Phase 1 results will finalize feasibility assessments for a novel instrument that enables an emerging MFH cancer treatment but for currently contraindicated patients, into clinical practice for human use, at a future stage.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Topic Code
MD
Solicitation Number
NSF 23-515
Status
(Complete)
Last Modified 9/25/24
Period of Performance
10/1/24
Start Date
9/30/25
End Date
Funding Split
$275.0K
Federal Obligation
$0.0
Non-Federal Obligation
$275.0K
Total Obligated
Activity Timeline
Additional Detail
Award ID FAIN
2404556
SAI Number
None
Award ID URI
SAI EXEMPT
Awardee Classifications
Small Business
Awarding Office
491503 TRANSLATIONAL IMPACTS
Funding Office
491503 TRANSLATIONAL IMPACTS
Awardee UEI
DSHNXJQWSRD7
Awardee CAGE
None
Performance District
PR-98
Modified: 9/25/24