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2321456

Project Grant

Overview

Grant Description
Sttr Phase I: Innovative Expandable Dental Sealer - The Broader Impact/Commercial Potential of this Small Business Technology Transfer (STTR) Phase I project is in developing a novel dental sealer technology for root canal treatments for endodontists and general dentists.

The complex and inaccessible nature of the root canal system causes 65% of root canal fillings to fail. Expandable dental sealers used during root canal treatments provide an effective solution by filling the gaps in the canal space by preventing leakage, enabling clinicians to perform the procedure with greater ease and accuracy.

This project's commercial impact includes an addressable market of 22.3 million root canal treatments annually. The proposed innovation supports enhanced patient safety, reduced time at the dentists'/endodontists' office and decreased costs for patients, reduced risk of infection and retreatment, and advanced capabilities of clinicians through training.

This Small Business Technology Transfer (STTR) Phase I project will characterize the expansion and other properties of the patented elastomeric polyurethane sealer (EPS). The project will begin by generating a functionalized and optimized formula of the EPS using additive ingredients. The team will perform in vitro testing to evaluate the material's physicochemical properties.

Finally, the study will establish the in vivo histocompatibility of EPS using animal models and check its cytotoxicity, a key hurdle that must be overcome before clinical evaluation and Food and Drug Administration (FDA) registration. These studies will facilitate the development of an entirely new type of dental sealer.

This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria. - Subawards are planned for this award.
Awardee
Funding Goals
THE GOAL OF THIS FUNDING OPPORTUNITY, "NSF SMALL BUSINESS INNOVATION RESEARCH (SBIR)/ SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAMS PHASE I", IS IDENTIFIED IN THE LINK: HTTPS://WWW.NSF.GOV/PUBLICATIONS/PUB_SUMM.JSP?ODS_KEY=NSF23515
Place of Performance
Newark, New Jersey 07103-2757 United States
Geographic Scope
Single Zip Code
Afsartech was awarded Project Grant 2321456 worth $274,867 from in October 2023 with work to be completed primarily in Newark New Jersey United States. The grant has a duration of 1 year and was awarded through assistance program 47.084 NSF Technology, Innovation, and Partnerships. The Project Grant was awarded through grant opportunity Small Business Innovation Research/ Small Business Technology Transfer Program Phase I.

SBIR Details

Research Type
STTR Phase I
Title
STTR Phase I:Innovative Expandable Dental Sealer
Abstract
The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is in developing a novel dental sealer technology for root canal treatments for endodontists and general dentists. The complex and inaccessible nature of the root canal system causes 65% of root canal fillings to fail. Expandable dental sealers used during root canal treatments provide an effective solution by filling the gaps in the canal space by preventing leakage, enabling clinicians to perform the procedure with greater ease and accuracy. This project’s commercial impact includes an addressable market of 22.3 million root canal treatments annually. The proposed innovation supports enhanced patient safety, reduced time at the dentists'/endodontists' office and decreased costs for patients, reduced risk of infection and retreatment, and advanced capabilities of clinicians through training._x000D_ _x000D_ This Small Business Technology Transfer (STTR) Phase I project will characterize the expansion and other properties of the patented elastomeric polyurethane sealer (EPS). The project will begin by generating a functionalized and optimized formula of the EPS using additive ingredients. The team will perform in vitro testing to evaluate the material’s physicochemical properties. Finally, the study will establish the in vivo histocompatibility of EPS using animal models and check its cytotoxicity, a key hurdle that must be overcome before clinical evaluation and Food and Drug Administration (FDA) registration. These studies will facilitate the development of an entirely new type of dental sealer._x000D_ _x000D_ This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Topic Code
BM
Solicitation Number
NSF 23-515

Status
(Ongoing)

Last Modified 12/21/23

Period of Performance
10/1/23
Start Date
9/30/24
End Date
42.0% Complete

Funding Split
$274.9K
Federal Obligation
$0.0
Non-Federal Obligation
$274.9K
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to 2321456

Transaction History

Modifications to 2321456

Additional Detail

Award ID FAIN
2321456
SAI Number
None
Award ID URI
SAI EXEMPT
Awardee Classifications
Small Business
Awarding Office
491503 TRANSLATIONAL IMPACTS
Funding Office
491503 TRANSLATIONAL IMPACTS
Awardee UEI
JS7QTHJG7BG1
Awardee CAGE
None
Performance District
NJ-10
Senators
Robert Menendez
Cory Booker

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
Research and Related Activities, National Science Foundation (049-0100) General science and basic research Grants, subsidies, and contributions (41.0) $274,867 100%
Modified: 12/21/23