2303044
Cooperative Agreement
Overview
Grant Description
NSF Center for the Mechanical Control of Chemistry - The NSF Center for the Mechanical Control of Chemistry (CMCC) is an integrative research and training environment that brings together chemists, physicists, and engineers around the common goal of establishing a fundamental understanding of mechanchemistry - the use of mechanical force to drive chemical reactions.
Mechanochemistry offers a powerful and versatile means for chemical synthesis, opening the door to new reactions and new materials that cannot be made using traditional synthetic methods. While the effects of light, heat, and electric charge for driving chemical reactions are well understood, the use of mechanical force as a controlling synthetic element is far less developed.
To unveil the full potential of mechanchemistry, the CMCC aims to bridge key knowledge gaps between the fields of chemistry and mechanics which have limited the broad application of mechanchemistry as a core synthetic methodology. As mechanchemical reactions can often be carried out with little or no solvent, and at lower temperatures than traditional synthetic approaches, the translation of knowledge in the CMCC from molecular-scale understanding to large-scale syntheses has the potential for major technological and economic benefits globally, affording more sustainable approaches to the synthesis of chemicals and materials.
The CMCC is a coordinated effort among academic, industrial, and national lab partners who are seeking to advance fundamental science which will drive applications in the field of mechanchemistry. Through the development of an Integrated Toolset Program (ITP), the CMCC will advance both experimental and computational tools, establishing fundamental relationships between key reaction parameters and applied forces/stresses. This research aims to develop new chemical reactions and models for predictable mechanchemical syntheses in terms of reaction rates, product yields, and selectivity.
These new tools will be applied to advance our understanding of mechanchemical processes for chemical systems ranging from fundamental organic and organometallic reactions (Thrust 1) to solid-state materials, e.g. layered lanthanides, perovskites, and metal halides (Thrust 2). The interplay of synergistic activation mechanisms of force with light, heat, and charge is expected to expand understanding of this powerful approach to chemical synthesis.
Working with industrial partners, the CMCC seeks to translate this new understanding of force-dependent selectivity and reactivity into new reactor designs, with integrated force control for scale-up. Synergistic research carried out by members of the CMCC has the potential to yield disruptive technologies for the chemical and pharmaceutical industries.
To support this sea change, the CMCC will recruit and educate a diverse mechanchemistry workforce. CMCC trainees will be immersed in an inclusive and interdisciplinary environment, benefiting from new curricular developments, exposure to innovation and industrial collaborations, and engagement through extensive informal science communication efforts designed to connect with K-12 and public audiences. This will establish the CMCC as a premier global hub for mechanchemistry.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Mechanochemistry offers a powerful and versatile means for chemical synthesis, opening the door to new reactions and new materials that cannot be made using traditional synthetic methods. While the effects of light, heat, and electric charge for driving chemical reactions are well understood, the use of mechanical force as a controlling synthetic element is far less developed.
To unveil the full potential of mechanchemistry, the CMCC aims to bridge key knowledge gaps between the fields of chemistry and mechanics which have limited the broad application of mechanchemistry as a core synthetic methodology. As mechanchemical reactions can often be carried out with little or no solvent, and at lower temperatures than traditional synthetic approaches, the translation of knowledge in the CMCC from molecular-scale understanding to large-scale syntheses has the potential for major technological and economic benefits globally, affording more sustainable approaches to the synthesis of chemicals and materials.
The CMCC is a coordinated effort among academic, industrial, and national lab partners who are seeking to advance fundamental science which will drive applications in the field of mechanchemistry. Through the development of an Integrated Toolset Program (ITP), the CMCC will advance both experimental and computational tools, establishing fundamental relationships between key reaction parameters and applied forces/stresses. This research aims to develop new chemical reactions and models for predictable mechanchemical syntheses in terms of reaction rates, product yields, and selectivity.
These new tools will be applied to advance our understanding of mechanchemical processes for chemical systems ranging from fundamental organic and organometallic reactions (Thrust 1) to solid-state materials, e.g. layered lanthanides, perovskites, and metal halides (Thrust 2). The interplay of synergistic activation mechanisms of force with light, heat, and charge is expected to expand understanding of this powerful approach to chemical synthesis.
Working with industrial partners, the CMCC seeks to translate this new understanding of force-dependent selectivity and reactivity into new reactor designs, with integrated force control for scale-up. Synergistic research carried out by members of the CMCC has the potential to yield disruptive technologies for the chemical and pharmaceutical industries.
To support this sea change, the CMCC will recruit and educate a diverse mechanchemistry workforce. CMCC trainees will be immersed in an inclusive and interdisciplinary environment, benefiting from new curricular developments, exposure to innovation and industrial collaborations, and engagement through extensive informal science communication efforts designed to connect with K-12 and public audiences. This will establish the CMCC as a premier global hub for mechanchemistry.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Awardee
Funding Goals
THE GOAL OF THIS FUNDING OPPORTUNITY, "CENTERS FOR CHEMICAL INNOVATION", IS IDENTIFIED IN THE LINK: HTTPS://WWW.NSF.GOV/PUBLICATIONS/PUB_SUMM.JSP?ODS_KEY=NSF22596
Grant Program (CFDA)
Awarding / Funding Agency
Place of Performance
College Station,
Texas
77843-3255
United States
Geographic Scope
Single Zip Code
Related Opportunity
Analysis Notes
Amendment Since initial award the total obligations have increased 190% from $4,000,000 to $11,600,000.
Texas A & M University was awarded
NSF Center the Mechanical Control of Chemistry: Advancing Mechanoch
Cooperative Agreement 2303044
worth $11,600,000
from the Division of Chemistry in September 2023 with work to be completed primarily in College Station Texas United States.
The grant
has a duration of 5 years and
was awarded through assistance program 47.049 Mathematical and Physical Sciences.
The Cooperative Agreement was awarded through grant opportunity Centers for Chemical Innovation.
Status
(Ongoing)
Last Modified 9/10/25
Period of Performance
9/1/23
Start Date
8/31/28
End Date
Funding Split
$11.6M
Federal Obligation
$0.0
Non-Federal Obligation
$11.6M
Total Obligated
Activity Timeline
Subgrant Awards
Disclosed subgrants for 2303044
Transaction History
Modifications to 2303044
Additional Detail
Award ID FAIN
2303044
SAI Number
None
Award ID URI
SAI EXEMPT
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
490309 DIVISION OF CHEMISTRY
Funding Office
490309 DIVISION OF CHEMISTRY
Awardee UEI
JF6XLNB4CDJ5
Awardee CAGE
1T3H7
Performance District
TX-10
Senators
John Cornyn
Ted Cruz
Ted Cruz
Budget Funding
| Federal Account | Budget Subfunction | Object Class | Total | Percentage |
|---|---|---|---|---|
| Research and Related Activities, National Science Foundation (049-0100) | General science and basic research | Grants, subsidies, and contributions (41.0) | $4,000,000 | 100% |
Modified: 9/10/25