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2242812

Cooperative Agreement

Overview

Grant Description
RII Track-1: AI-Enabled Devices for the Advancement of Personalized and Transformative Healthcare in South Carolina

The vision of the Artificial Intelligence-Enabled Devices for the Advancement of Personalized and Transformative Healthcare in South Carolina (ADAPT) project is to build research capacity at the nexus of artificial intelligence (AI), life and social sciences, and bioengineering through fundamental research, education, workforce development, and industry partnerships. Building this capacity will significantly accelerate the development and deployment of AI solutions to create next-generation biomedical devices that will improve healthcare outcomes and address the healthcare needs of South Carolinians, especially those in underserved regions.

ADAPT will contribute to South Carolina's AI-enabled biomedical device industry by fostering cross-cutting STEM research throughout the state and translating research outcomes into new technologies. Participation in AI development and associated biomedical device research will be expanded by recruiting and supporting trainees from groups traditionally underrepresented through STEM camps, teacher engagement, and retention/persistence initiatives along the STEM pipeline.

ADAPT will be led by Clemson University in partnership with Benedict College, The Citadel, Claflin University, College of Charleston, Francis Marion University, Medical University of South Carolina, South Carolina Research Authority, South Carolina State University, Tri-County Technical College, University of South Carolina, and Winthrop University.

ADAPT research will focus on emerging biomedical AI and its integration with targeted biomedical devices for use in three phases of medical interventions: diagnosis, treatment, and rehabilitation. The AI-enabling core will take on fundamental research in biomedical AI, tackling issues such as data acquisition, multimodal data fusion, data representation learning, meta-learning, physics-informed machine learning, security, and trustworthy AI to provide integrated solutions for the biomedical devices developed in each research thrust.

The AI ethics team in ADAPT's AI-enabling core is tasked to set AI ethics standards and design innovative education and training programs to ensure that the AI-enabled biomedical devices are trusted by both healthcare providers and receivers in practice. Research will address critical issues in biomedical AI, including incorporation of ethics into design decisions; elimination of the "black box" via explainable AI; integration of multimodal data via deep learning models; and AI-device integration via digital twins.

ADAPT will deliver a new national model for developing biomedical devices, educating and training a biomedical AI workforce, and interacting with stakeholders. ADAPT will benefit the state of South Carolina through: (1) leadership and national prominence in healthcare AI; (2) an AI-literacy campaign to promote the use of AI in addressing healthcare disparities; (3) social awareness of the importance of AI in precision medicine; and (4) professional competency in AI through continuing education credits for healthcare professionals (e.g., nurses, physicians, and healthcare administrators).

This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Funding Goals
THE GOAL OF THIS FUNDING OPPORTUNITY, "EPSCOR RESEARCH INFRASTRUCTURE IMPROVEMENT PROGRAM TRACK-1", IS IDENTIFIED IN THE LINK: HTTPS://WWW.NSF.GOV/PUBLICATIONS/PUB_SUMM.JSP?ODS_KEY=NSF22599
Grant Program (CFDA)
Place of Performance
Clemson, South Carolina 29634-0001 United States
Geographic Scope
Single Zip Code
Analysis Notes
Amendment Since initial award the total obligations have increased 164% from $5,126,834 to $13,525,016.
Clemson University was awarded AI-Enabled Devices for Personalized Healthcare in SC Cooperative Agreement 2242812 worth $13,525,016 from the NSF Office of Integrative Activities in August 2023 with work to be completed primarily in Clemson South Carolina United States. The grant has a duration of 5 years and was awarded through assistance program 47.083 Integrative Activities. The Cooperative Agreement was awarded through grant opportunity EPSCoR Research Infrastructure Improvement Program Track-1.

Status
(Ongoing)

Last Modified 8/12/25

Period of Performance
8/1/23
Start Date
7/31/28
End Date
41.0% Complete

Funding Split
$13.5M
Federal Obligation
$0.0
Non-Federal Obligation
$13.5M
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to 2242812

Transaction History

Modifications to 2242812

Additional Detail

Award ID FAIN
2242812
SAI Number
None
Award ID URI
SAI EXEMPT
Awardee Classifications
Public/State Controlled Institution Of Higher Education
Awarding Office
490106 OFFICE OF INTEGRATIVE ACTIVITIES
Funding Office
490106 OFFICE OF INTEGRATIVE ACTIVITIES
Awardee UEI
H2BMNX7DSKU8
Awardee CAGE
1D5U5
Performance District
SC-03
Senators
Lindsey Graham
Tim Scott

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
Research and Related Activities, National Science Foundation (049-0100) General science and basic research Grants, subsidies, and contributions (41.0) $5,126,834 100%
Modified: 8/12/25