2212728
Project Grant
Overview
Grant Description
Sttr Phase I: Electronic Measurement of Capillary Refill Time to Improve Outcomes from Sepsis - The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is a novel external system for rapidly diagnosing sepsis by measuring capillary refill time (CRT).
Independent clinical studies have demonstrated the utility of CRT for detecting sepsis. Current methods for monitoring capillary refill times rely on physical examinations that are both prone to human error and inconsistency.
The company aims to develop an automated diagnostic and monitoring device for objectively and repeatably quantifying capillary refill time for use in a clinical setting. If successful, the technology may have widespread potential use in emergency departments, clinics, ambulances, or at home.
This Small Business Technology Transfer (STTR) Phase I project develops a new finger-sensor interface for monitoring CRT that ensures contact between the finger and sensor across a range of finger sizes and validate the system in human use.
The objectives are to ensure human factors engineering to enable use in a broad range of patients by a wide range of caregivers. A novel algorithm to improve sensor performance and provide user feedback on noise or aberrant signals will also be integrated.
The system will be tested in a group of patients at risk for sepsis to demonstrate the device reliably and accurately measures the CRT across a wide variety of patient demographics and the device is easily usable by a wide range of caregivers including physicians and family members without extensive training.
A successful Phase I outcome is a system enabling the consistent ability to collect high-quality measures of CRT in patients at risk for sepsis and to provide the user with ongoing measures of signal quality.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Independent clinical studies have demonstrated the utility of CRT for detecting sepsis. Current methods for monitoring capillary refill times rely on physical examinations that are both prone to human error and inconsistency.
The company aims to develop an automated diagnostic and monitoring device for objectively and repeatably quantifying capillary refill time for use in a clinical setting. If successful, the technology may have widespread potential use in emergency departments, clinics, ambulances, or at home.
This Small Business Technology Transfer (STTR) Phase I project develops a new finger-sensor interface for monitoring CRT that ensures contact between the finger and sensor across a range of finger sizes and validate the system in human use.
The objectives are to ensure human factors engineering to enable use in a broad range of patients by a wide range of caregivers. A novel algorithm to improve sensor performance and provide user feedback on noise or aberrant signals will also be integrated.
The system will be tested in a group of patients at risk for sepsis to demonstrate the device reliably and accurately measures the CRT across a wide variety of patient demographics and the device is easily usable by a wide range of caregivers including physicians and family members without extensive training.
A successful Phase I outcome is a system enabling the consistent ability to collect high-quality measures of CRT in patients at risk for sepsis and to provide the user with ongoing measures of signal quality.
This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Awardee
Funding Goals
THE GOAL OF THIS FUNDING OPPORTUNITY, "SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAM PHASE I", IS IDENTIFIED IN THE LINK: HTTPS://WWW.NSF.GOV/PUBLICATIONS/PUB_SUMM.JSP?ODS_KEY=NSF21563
Grant Program (CFDA)
Awarding Agency
Place of Performance
Portland,
Oregon
97239-3011
United States
Geographic Scope
Single Zip Code
Related Opportunity
21-563
Analysis Notes
Amendment Since initial award the End Date has been extended from 01/31/24 to 06/30/24.
Promedix was awarded
Project Grant 2212728
worth $255,750
from in February 2023 with work to be completed primarily in Portland Oregon United States.
The grant
has a duration of 1 year 4 months and
was awarded through assistance program 47.084 NSF Technology, Innovation, and Partnerships.
SBIR Details
Research Type
STTR Phase I
Title
STTR Phase I:Electronic Measurement of Capillary Refill Time to Improve Outcomes from Sepsis
Abstract
The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is a novel external system for rapidly diagnosing sepsis by measuring capillary refill time (CRT). Independent clinical studies have demonstrated the utility of CRT for detecting sepsis. Current methods for monitoring capillary refill times rely on physical examinations that are both prone to human error and inconsistency. The company aims to develop an automated diagnostic and monitoring device for objectively and repeatably quantifying capillary refill time for use in a clinical setting. If successful, the technology may have widespread potential use in emergency departments, clinics, ambulances, or at home._x000D__x000D_ This Small Business Technology Transfer (STTR) Phase I project develops a new finger-sensor interface for monitoring CRT that ensures contact between the finger and sensor across a range of finger sizes and validate the system in human use. The objectives are to ensure human factors engineering to enable use in a broad range of patients by a wide range of caregivers. A novel algorithm to improve sensor performance and provide user feedback on noise or aberrant signals will also be integrated. The system will be tested in a group of patients at risk for sepsis to demonstrate the device reliably and accurately measures the CRT across a wide variety of patient demographics and the device is easily usable by a wide range of caregivers including physicians and family members without extensive training. A successful Phase I outcome is a system enabling the consistent ability to collect high-quality measures of CRT in patients at risk for sepsis and to provide the user with ongoing measures of signal quality._x000D_ _x000D_ This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Topic Code
MD
Solicitation Number
NSF 21-563
Status
(Complete)
Last Modified 4/4/24
Period of Performance
2/15/23
Start Date
6/30/24
End Date
Funding Split
$255.8K
Federal Obligation
$0.0
Non-Federal Obligation
$255.8K
Total Obligated
Activity Timeline
Transaction History
Modifications to 2212728
Additional Detail
Award ID FAIN
2212728
SAI Number
None
Award ID URI
SAI EXEMPT
Awardee Classifications
Small Business
Awarding Office
491503 TRANSLATIONAL IMPACTS
Funding Office
491503 TRANSLATIONAL IMPACTS
Awardee UEI
GKUNY11BL5D4
Awardee CAGE
8AVU3
Performance District
OR-01
Senators
Jeff Merkley
Ron Wyden
Ron Wyden
Budget Funding
| Federal Account | Budget Subfunction | Object Class | Total | Percentage |
|---|---|---|---|---|
| Research and Related Activities, National Science Foundation (049-0100) | General science and basic research | Grants, subsidies, and contributions (41.0) | $255,750 | 100% |
Modified: 4/4/24