Search Prime Grants


Project Grant


Grant Description
Sbir Phase I: Motion Artifact Management for Accurate and Continuous Non-Invasive Blood Pressure Monitoring -The Broader Impact/Commercial Potential of This Small Business Innovation Research (SBIR) Phase I Project Is to Enable Accurate, Continuous, and Widely Available Blood Pressure (BP) Measurements.

The Current Standard of Care Is Single Point-in-Time BP Monitoring Using an Arm-Cuff Device. This Method Has Two Basic Drawbacks: Inaccuracy and the Inability to Measure BP Continuously Over 24 Hours, Limiting Clinical Insight.

The Major Challenge to Continuous Reliable BP Measurements Is Motion Artifacts Due to Movement, Such as an Arm Gestures. This Project Will Advance Development of a Novel Device for Non-Invasive Beat-to-Beat BP Measurement in a Cuff-Less, Wrist-Wearable Device.

Accurate 24-Hour BP Measurement at Home and Other Settings Will Significantly Improve Outcomes for 1.5 Billion People Globally Who Suffer from Chronic High BP or Hypertension, a Leading Cause of Stroke and Heart Attacks. Other Chronic Conditions Benefiting from Accurate 24-Hour BP Measurement Include Sleep Apnea, Heart and Renal Failure, and Dementia.

This Small Business Innovation Research (SBIR) Phase I Project Utilizes a Highly Sensitive Optomechanical Sensor to Capture Video Images of Skin Displacement Over the Radial Artery to Independently Measure Systolic and Diastolic BP Continuously. The Technology Measures BP Accurately and Continuously in Stationary Conditions (I.E., Seated or Lying Down).

The Goal of This Project Is to Identify, Characterize and Address Motion Artifacts That Occur During Routine Use in Hospital Intensive Care Units and Operating Rooms.

This Award Reflects NSF's Statutory Mission and Has Been Deemed Worthy of Support Through Evaluation Using the Foundation's Intellectual Merit and Broader Impacts Review Criteria.
Grant Program (CFDA)
Place of Performance
Needham Heights, Massachusetts 02494-2887 United States
Geographic Scope
Single Zip Code
Related Opportunity
Dynocardia was awarded Project Grant 2151591 worth $256,000 from Directorate for Technology, Innovation and Partnerships in March 2022 with work to be completed primarily in Needham Heights Massachusetts United States. The grant has a duration of 1 year and was awarded through assistance program 47.041 Engineering.

SBIR Details

Research Type
SBIR Phase I
SBIR Phase I:Motion artifact management for accurate and continuous non-invasive blood pressure monitoring
The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to enable accurate, continuous, and widely available blood pressure (BP) measurements. The current standard of care is single point-in-time BP monitoring using an arm-cuff device. This method has two basic drawbacks: inaccuracy and the inability to measure BP continuously over 24 hours, limiting clinical insight. The major challenge to continuous reliable BP measurements is motion artifacts due to movement, such as an arm gestures.This project will advance development of a novel device for non-invasive beat-to-beat BP measurement in a cuff-less, wrist-wearable device.Accurate 24-hour BP measurement at home and other settings will significantly improve outcomes for 1.5 billion people globally who suffer from chronic high BP or hypertension, a leading cause of stroke and heart attacks. Other chronic conditions benefiting from accurate 24-hour BP measurement include sleep apnea, heart and renal failure, and dementia.This Small Business Innovation Research (SBIR) Phase I project utilizes a highly sensitive optomechanical sensor to capture video images of skin displacement over the radial artery to independently measure systolic and diastolic BP continuously. The technology measures BP accurately and continuously in stationary conditions (i.e., seated or lying down). The goal of this project is to identify, characterize and address motion artifacts that occur during routine use in hospital intensive care units and operating rooms.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Topic Code
Solicitation Number
NSF 21-562


Last Modified 3/2/22

Period of Performance
Start Date
End Date
100% Complete

Funding Split
Federal Obligation
Non-Federal Obligation
Total Obligated
100.0% Federal Funding
0.0% Non-Federal Funding

Activity Timeline

Interactive chart of timeline of amendments to 2151591

Additional Detail

SAI Number
Award ID URI
Awardee Classifications
Small Business
Awarding Office
Funding Office
Awardee UEI
Awardee CAGE
Performance District
Edward Markey
Elizabeth Warren
Jake Auchincloss

Budget Funding

Federal Account Budget Subfunction Object Class Total Percentage
Research and Related Activities, National Science Foundation (049-0100) General science and basic research Grants, subsidies, and contributions (41.0) $256,000 100%
Modified: 3/2/22