2136163
Project Grant
Overview
Grant Description
SBIR Phase I: Genomics and AI-Based Biological Effect Benchmark Development for Functional Ingredients - The broader impact of this Small Business Innovation Research (SBIR) Phase I project is to improve the consistency of functional food and beverage and dietary supplements (FFBDS). Functional ingredients are ingredients that have benefits beyond normal nutrition, such as curcumin (turmeric), green tea, and cranberry extract.
Currently, FFBDS companies face challenges in sourcing functional ingredients that are consistent in their quality from batch-to-batch. The testing methods measure only the ingredient quantity and not quality. This project advances a technology to measure the effectiveness of these functional ingredients. This information enables FFBDS manufacturers to provide clarity, trust, and ease to the process of purchasing functional products. Furthermore, this can also be used to identify the specific health benefits and develop personalized nutrition products.
In addition, the data can provide traceability and information for sustainable farming, harvesting, extracting, and manufacturing practices. The proposed project will develop biological effect benchmarks for the pure form of functional ingredients, starting with turmeric, using commercially available human cells, genomics, and artificial intelligence technologies. The project will develop a test to measure a compound's biological effectiveness compared to that of the benchmark.
The system will generate a biological effect score of the ingredient, a list of key genes affected, and a description of the relevance of these genes on human health. The system will be developed for high-throughput, cost-effective operation. This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Currently, FFBDS companies face challenges in sourcing functional ingredients that are consistent in their quality from batch-to-batch. The testing methods measure only the ingredient quantity and not quality. This project advances a technology to measure the effectiveness of these functional ingredients. This information enables FFBDS manufacturers to provide clarity, trust, and ease to the process of purchasing functional products. Furthermore, this can also be used to identify the specific health benefits and develop personalized nutrition products.
In addition, the data can provide traceability and information for sustainable farming, harvesting, extracting, and manufacturing practices. The proposed project will develop biological effect benchmarks for the pure form of functional ingredients, starting with turmeric, using commercially available human cells, genomics, and artificial intelligence technologies. The project will develop a test to measure a compound's biological effectiveness compared to that of the benchmark.
The system will generate a biological effect score of the ingredient, a list of key genes affected, and a description of the relevance of these genes on human health. The system will be developed for high-throughput, cost-effective operation. This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Awardee
Grant Program (CFDA)
Awarding Agency
Place of Performance
Rochester,
Minnesota
55902-3125
United States
Geographic Scope
Single Zip Code
Related Opportunity
None
Canomiks was awarded
Project Grant 2136163
worth $256,000
from Directorate for Technology, Innovation and Partnerships in April 2022 with work to be completed primarily in Rochester Minnesota United States.
The grant
has a duration of 1 year and
was awarded through assistance program 47.041 Engineering.
SBIR Details
Research Type
SBIR Phase I
Title
SBIR Phase I:Genomics and AI-based biological effect benchmark development for functional ingredients
Abstract
The broader impact of this Small Business Innovation Research (SBIR) Phase I project is to improve the consistency of functional food and beverage and dietary supplements (FFBDS).Functional ingredients are ingredients that have benefits beyond normal nutrition, such as curcumin (turmeric), green tea, and cranberry extract. Currently FFBDS companies face challenges in sourcing functional ingredients that are consistent in their quality from batch-to-batch. The testing methods measure only the ingredient quantity and not quality. This project advances a technology to measure the effectiveness of these functional ingredients.This information enables FFBDS manufacturers to provide clarity, trust, and ease to the process of purchasing functional products. Furthermore, this can also be used to identify the specific health benefits and develop personalized nutrition products. In addition, the data can provide traceability and information for sustainable farming, harvesting, extracting, and manufacturing practices.The proposed project will develop biological effect benchmarks for the pure form of functional ingredients, starting with turmeric, using commercially available human cells, genomics, and artificial intelligence technologies.The project will develop a test to measures a compound's biological effectiveness compared to that of the benchmark. The system will generate a biological effect score of the ingredient, a list of key genes affected, and a description of the relevance of these genes on human health. The system will be developed for high-throughput, cost-effective operation.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
Topic Code
BT
Solicitation Number
NSF 21-562
Status
(Complete)
Last Modified 4/5/22
Period of Performance
4/1/22
Start Date
3/31/23
End Date
Funding Split
$256.0K
Federal Obligation
$0.0
Non-Federal Obligation
$256.0K
Total Obligated
Activity Timeline
Additional Detail
Award ID FAIN
2136163
SAI Number
None
Award ID URI
SAI EXEMPT
Awardee Classifications
Small Business
Awarding Office
491503 TRANSLATIONAL IMPACTS
Funding Office
490707 DIVISION OF INDUSTRIAL INNOVATION
Awardee UEI
TPWWJD1AD8N3
Awardee CAGE
8WJQ3
Performance District
01
Senators
Amy Klobuchar
Tina Smith
Tina Smith
Representative
Brad Finstad
Budget Funding
| Federal Account | Budget Subfunction | Object Class | Total | Percentage |
|---|---|---|---|---|
| Research and Related Activities, National Science Foundation (049-0100) | General science and basic research | Grants, subsidies, and contributions (41.0) | $256,000 | 100% |
Modified: 4/5/22