Type 1 Diabetes TrialNet Clinical Network Hub (U01 Clinical Trial Not Allowed)

Background
The Type 1 Diabetes TrialNet Clinical Network Hub (HUB) is a screening and clinical activities coordination unit for clinical trials focusing on the prevention of and early intervention in type 1 diabetes (T1D). The main objective of the HUB is to increase the efficiency and productivity of the TrialNet network by providing coordination of communications and outreach and developing new tools and approaches to increase screening, recruitment, and retention.

Grant Details
The HUB is responsible for enhancing risk screening, trial recruitment outreach, supporting clinical trial and ancillary studies operations, enhancing administration/leadership, organizing future goals, and executing excellent communication and coordination. The HUB will also work on increasing diversity among TrialNet participants. The HUB will participate in the oversight of clinical aspects related to the development and implementation of trials over the funding period.

Eligibility Requirements
The Program Director/Principal Investigator (PD/PI) must be a physician and clinical trialist with an extensive track record for recruiting and enrolling individuals into multi-center clinical trials in T1D prevention. Eligible applicants include higher education institutions, nonprofits, for-profit organizations, state governments, county governments, city or township governments, special district governments, Indian/Native American Tribal Governments (Federally Recognized), U.S. Territory or Possession, independent school districts, public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), faith-based or community-based organizations.

Period of Performance
The project period is 5 years starting from October 17, 2024. The application budget is limited to approximately $750,000 per year in direct costs.

Grant Value
$1,000,000 is intended to be committed in FY 2025 to fund 1 award. The award budget for all years may vary based on available funds and network activity.