The National Drug Abuse Treatment Clinical Trials Network (UG1 Clinical Trial Required)

Background
The National Drug Abuse Treatment Clinical Trials Network (CTN) was established in 1999 to bridge the gap between research and practice to improve substance use disorder (SUD) treatment. The CTN seeks to address critical research questions with direct relevance to clinical practice and the needs of people with SUDs. The CTN currently is comprised of 16 Nodes, a Data and Statistics Center (DSC), and a Clinical Coordinating Center (CCC). Each Node is a primary performance site, with numerous affiliated clinical research sites. The CTN program is administered within NIDA through the Center for the Clinical Trials Network (CCTN). NIDA plans to continue supporting the CTN research infrastructure to build on the broad portfolio of research conducted in the CTN.

Grant Details
This notice of funding opportunity (NOFO) invites applications from clinical investigators to participate in the National Drug Abuse Treatment Clinical Trials Network (CTN) and contribute to the network's capacity to respond to urgent public health needs. The NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications should address how their proposed Node infrastructure, including the expertise of investigators and institutional resources, could contribute to addressing key and emerging substance misuse/SUD issues in a variety of healthcare settings.

The proposed infrastructure and research agenda should illustrate how the proposed Node could participate in the research network to improve SUD treatment and advance research in the field.

Eligibility Requirements
All organizations administering an eligible parent award may apply for a supplement under this NOFO. Eligible organizations include higher education institutions, nonprofits, for-profit organizations, local governments, state governments, federal government agencies, U.S. territories or possessions, independent school districts, public housing authorities/Indian housing authorities, Native American tribal organizations, faith-based or community-based organizations, and regional organizations.

Period of Performance
The period of performance is seven years.

Grant Value
$12,000,000 in total funds in FY 2025 to fund up to 16 awards. Application budgets are limited to $500,000 per year in direct costs.