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Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)

ID: RFA-CA-27-021 • Type: Posted
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Description

Posted:
This Notice of Funding Opportunity (NOFO) solicits applications for the continued development and sustainment of high value informatics research resources to improve the acquisition, management, analysis, and dissemination of data and knowledge across the cancer research continuum including cancer biology, cancer treatment and diagnosis, early cancer detection, risk assessment and prevention, cancer control and epidemiology. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Program, this NOFO is focused on sustaining operations and maintaining and evolving the scientific relevance of existing, widely-adopted informatics tools and resources. This is in contrast to early-stage and advanced development efforts to generate these tools and resources that will be supported by companion ITCR NOFOs. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, the application must provide clear justification for why the research resource should be maintained and how it has benefited and will continue to benefit the cancer research field. In addition, mechanisms for assessing and maximizing the value of the resource to researchers and supporting close engagement between the resource and the targeted research community should be described.This NOFO invites applications to support the sustained operations of informatics technology resources that support a wide range of cancer research, including discovery biology, population studies, as well as clinical and translational research. The emphasis is on sustaining resources that have had a demonstrated impact on cancer research. In addition, all projects proposed in response to this NOFO must involve the following general attributes:Evidence that the technology has had significant impact on cancer research to date and the sustainment plan will lead to the continued advancement of cancer researchRobust plans for supporting the end-user community including documentation, training, and other outreach activitiesClear processes for engaging end users to address emerging needs of the targeted research communities to ensure that the research resource maintains relevance to the research it supports
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Background
This Notice of Funding Opportunity (NOFO) is issued by the National Cancer Institute (NCI) as part of the Informatics Technology for Cancer Research (ITCR) Program. The mission of the ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research.

The goal of this NOFO is to solicit applications for the continued development and sustainment of high-value informatics research resources that improve data acquisition, management, analysis, and dissemination across various aspects of cancer research including biology, treatment, diagnosis, early detection, risk assessment, prevention, control, and epidemiology.

Grant Details
The grant supports sustained operations of informatics technology resources that have demonstrated impact on cancer research. Applications must provide evidence of significant impact to date and a sustainment plan that leads to continued advancement in cancer research.

Key tasks include:
- Developing robust plans for supporting end-user communities through documentation, training, and outreach activities.
- Establishing clear processes for engaging end users to address emerging needs.
- Participating in collaborative research activities post-award to enhance utility and interoperability of supported technologies.
- Engaging in community outreach and user training.
- Providing user help desk support and maintaining software stability and security.

Eligibility Requirements
Eligible applicants include higher education institutions (public/state controlled and private), nonprofits (with or without 501(c)(3) status), for-profit organizations (including small businesses), local/state governments, Indian/Native American tribal governments, federal agencies, independent school districts, public housing authorities, faith-based organizations, regional organizations, foreign organizations/collaborations, and non-domestic entities.

Period of Performance
The maximum project period is five years with an anticipated start date of July 1, 2026.

Grant Value
NCI intends to commit $1,800,000 in FY 2027 to fund 2 awards with budgets limited to $600,000 direct costs per year.

Place of Performance
The specific geographic locations are implied to be within the United States as part of the NCI's initiatives.
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Overview

Agency
National Institutes of Health (NIH) [HHS]
Category of Funding
Health
Funding Instruments
Cooperative Agreement
Grant Program (CFDA)
93.393 - Cancer Cause and Prevention Research
93.394 - Cancer Detection and Diagnosis Research
93.395 - Cancer Treatment Research
93.396 - Cancer Biology Research
93.399 - Cancer Control
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
Grants.gov
On 5/21/26 the National Institutes of Health posted grant opportunity RFA-CA-27-021 for Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional) with funding of $1.8 million. The grant will be issued under grant program 93.393 Cancer Cause and Prevention Research. It is expected that 2 total grants will be made worth between $50,000 and $600,000.

Timing

Posted Date
Closing Date
Due in 72 Days
Last Updated
Version
1
Archive Date

Eligibility

Eligible Applicants
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Special district governments
Independent school districts
Private institutions of higher education
For profit organizations other than small businesses
Native American tribal governments (Federally recognized)
Small businesses
State governments
County governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Public and State controlled institutions of higher education
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
City or township governments
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Info
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Award Sizing

Ceiling
$600,000
Floor
$50,000
Estimated Program Funding
$1,800,000
Estimated Number of Grants
2

Contacts

Contact
National Institutes of Health
Contact Email
nciitcr@mail.nih.gov
Email Description
juli.klemm@gmail.com
Contact Phone
(301) 402-2541

Documents

Posted documents for RFA-CA-27-021

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