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Single Source Renewal for the Continuation of the Liver Cirrhosis Network: Scientific and Data Coordination Center (U24 Clinical Trial Optional)

ID: RFA-DK-26-309 • Type: Posted
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Description

Posted: Jan. 9, 2026, 12:00 a.m. EST
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) of the U.S. Department of Health and Human Services is seeking a Single Source renewal application to continue scientific service as the Scientific and Data Coordination Center for the Liver Cirrhosis Network.The application will be peer-reviewed and if it is not a meritorious application, it will not be funded. This is a Notice of Funding Opportunity (NOFO) for a Single Source that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.
Posted: May 13, 2025, 12:00 a.m. EDT
Posted: May 13, 2025, 12:00 a.m. EDT
Posted: May 13, 2025, 12:00 a.m. EDT
Posted: May 13, 2025, 12:00 a.m. EDT
Posted: May 13, 2025, 12:00 a.m. EDT
Background
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) is issuing a Single Source renewal application to continue scientific service as the Scientific and Data Coordination Center for the Liver Cirrhosis Network. This initiative aims to address the significant public health burden posed by liver cirrhosis, which is a result of various chronic liver diseases.

The NIDDK established the Liver Cirrhosis Network to improve understanding of clinical and translational aspects of liver fibrosis and cirrhosis, including pro- and anti-fibrotic mechanisms.

Grant Details
The primary tasks under this grant include:
1. Completing enrollment in the Liver Cirrhosis Network Cohort and the Rosuvastatin Efficacy and Safety for Cirrhosis in the United States clinical studies.
2. Providing scientific coordination, data management, statistical analysis, and logistical support for ongoing studies.
3. Supporting manuscript preparation and organizing committee meetings.
4. Coordinating biospecimen tracking, distribution, and depositing into the NIDDK Data and Biospecimen Repository.
5. Ensuring compliance with regulatory policies regarding human subjects research.

Eligibility Requirements
Only Northwestern University is eligible to apply for this single source funding opportunity. Non-domestic entities are not eligible to apply.

Period of Performance
The maximum project period is 5 years, with an anticipated start date in July 2026.

Grant Value
$1,850,000 is intended to fund one award under this opportunity.

Place of Performance
The grant will be performed primarily at Northwestern University.
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Overview

Agency
National Institutes of Health (NIH) [HHS]
Category of Funding
Health
Funding Instruments
Cooperative Agreement
Grant Program (CFDA)
93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
Grants.gov
On 1/9/26 the National Institutes of Health posted grant opportunity RFA-DK-26-309 for Single Source Renewal for the Continuation of the Liver Cirrhosis Network: Scientific and Data Coordination Center (U24 Clinical Trial Optional) with funding of $1.9 million. The grant will be issued under grant program 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research. It is expected that one grant will be made.

Timing

Posted Date
Jan. 9, 2026, 12:00 a.m. EST
Closing Date
Jan. 27, 2027, 12:00 a.m. EST Due in 321 Days
Last Updated
Jan. 9, 2026, 10:56 a.m. EST
Version
1
Archive Date
March 29, 2027

Eligibility

Eligible Applicants
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Info
Refer to Section III. Eligibility Information within the NOFO for additional information on eligibility.Eligible OrganizationsOnly the following applicant is eligible to apply for this single source funding: Northwestern University. Please refer to Section I. Notice of Funding Opportunity Information for more details.Foreign Organizations/Foreign CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Award Sizing

Ceiling
$1,850,000
Floor
Not Listed
Estimated Program Funding
$1,850,000
Estimated Number of Grants
1

Contacts

Contact
National Institutes of Health
Contact Email
niddk_ddn@nih.gov   Profile
Contact Phone
(301) 402-2541

Documents

Posted documents for RFA-DK-26-309

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