Research Opportunities in Cancer Epidemiology Cohort Studies (U01 Clinical Trial Not Allowed)

Background
The National Cancer Institute (NCI) of the National Institutes of Health (NIH) is issuing this Notice of Funding Opportunity (NOFO) to support research in cancer epidemiology cohort studies. The goal is to address specific knowledge gaps in cancer etiology and survivorship, ultimately aiming to reduce cancer risk, incidence, morbidity, and mortality while enhancing the quality of life for cancer survivors.

Grant Details
The grant supports hypothesis-based research that includes:
1) Support for cohort infrastructure and maintenance;
2) Continued follow-up of participants;
3) Sharing of data and biospecimen resources;
4) Research studies within established cancer epidemiology cohorts;
5) Establishment of new cohorts or expansion of existing ones.

Successful applications must address scientific gaps in cancer epidemiology research and enhance understanding of cancer risk among healthy populations or outcomes among cancer survivors. Specific tasks include defining research gaps, demonstrating innovation in population and exposure measurement, justifying study populations and sample sizes, outlining plans for long-term sustainability, and ensuring community engagement.

Eligibility Requirements
Eligible applicants include higher education institutions, nonprofits, for-profit organizations, local governments, state governments, tribal governments, foreign organizations, and community-based organizations. Applicants must have the necessary skills and resources to carry out the proposed research. There are no cost-sharing requirements.

Period of Performance
The maximum project period is 5 years. The earliest start date for awarded projects is October 05, 2026.

Grant Value
Application budgets are not limited but must reflect the actual needs of the proposed project. The number of awards will depend on NIH appropriations and the submission of meritorious applications.