Research on Community Level Interventions for Firearm and Related Violence, Injury and Mortality Prevention (CLIF-VP) (UG3/UH3 Clinical Trial Optional)

Violence affects people of all ages and its impact is far-reaching. It is a leading cause of death and nonfatal injuries in the United States and constitutes a major public health crisis, especially among young people, and in particular among racial/ethnic minority, sexual and gender minority (SGM) and disability populations. Firearm homicide is the third leading cause of death among persons aged 10 to 24 years and the leading cause of death among Black men (45 years of age). NIH is committed to supporting research that identifies innovative prevention approaches to reduce firearm and related violence, injury and mortality. Within the legislative mandates and limitations of NIH funding (NOT-OD-21-058, NOT-OD-21-056), this initiative will support a network of research projects to develop and test interventions at the community or community organization level that aim to prevent firearm and related violence, injury and mortality.This FOA solicits bi-phasic research projects proposed in UG3/UH3 Phased Innovation Awards Cooperative Agreement applications. Funding for the UG3 phase (phase I) will be used to demonstrate sufficient preparation, feasibility and capacity to meet foundational milestone targets specific to the work proposed. A UG3 project that meets its milestones will be administratively considered by NIH and prioritized for transition to the UH3 award phase II). Applicants responding to this FOA must address specific aims and milestones for both the UG3 and UH3 phases.