Research Coordinating Center on the Exposome and Alzheimer's Disease (AD) and AD-Related Dementias (ADRD): Elucidating the Role of Social and Behavioral Determinants of Health in AD/ADRD Etiology and Disparities (U24 Clinical Trial Not Allowed)

Background
The purpose of this Funding Opportunity Announcement (FOA) is to invite applications to establish a coordinating center that will serve as a centralized hub for accessing, harmonizing, linking, and sharing environmental contextual data and individual exposure data with NIA/NIH-funded projects. This aims to foster collaboration and accelerate life course research on the social, behavioral, psychological, and economic exposures that shape Alzheimer’s disease (AD) and AD-related dementias (ADRD) outcomes and inequities.

Grant Details
Applications to establish the AD/ADRD Exposome Coordinating Center should identify five to seven social, behavioral, psychological, and economic exposome domains relevant to AD/ADRD. The center must develop an organizational and governance structure to support the administration, innovation, and dissemination functions. It should propose activities to establish guidance and practices for the use and harmonization of exposure data across NIA-supported infrastructure projects and other longitudinal studies of aging. Additionally, it should propose and support activities for the development of innovative and novel exposure measures and data. The center is also expected to disseminate resources and products developed by the AD/ADRD Exposome Coordinating Center to the broader AD/ADRD research community.

Eligibility Requirements
Eligible applicants include higher education institutions, nonprofits, for-profit organizations, state governments, county governments, city or township governments, special district governments, Indian/Native American Tribal Governments (Federally Recognized), independent school districts, public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), faith-based or community-based organizations, regional organizations. Foreign institutions are not eligible to apply.

Period of Performance
The project period can be up to 5 years. The earliest start date is October 27, 2023.

Grant Value
NIA intends to commit $5,000,000 in FY 2024 to fund 1 award. Application budgets are limited to $5,000,000 in total costs per year.