Personal Health Informatics for Delivering Actionable Insights to Individuals (R01 Clinical Trial Optional)

Background
The National Library of Medicine (NLM) and the National Institutes of Health (NIH) are issuing this Notice of Funding Opportunity (NOFO) to advance the development of novel informatics and data science approaches aimed at helping individuals understand and improve their health through actionable insights.

This initiative aligns with the 2017-2027 NLM Strategic Plan, which envisions personal data collection as a foundation for self-knowledge and health management. The goal is to provide meaningful insights through innovative personal health data collection, integration, analysis, and personalized risk assessments.

Grant Details
This NOFO invites research grant applications that will advance innovative informatics and data science approaches to help individuals understand and improve their health through actionable insights. Applications should focus on:

1. Developing tools, systems, or platforms that present results, interpretations, and limitations of personalized assessments effectively.
2. Engaging end users in the design process to ensure tools are generalizable, reusable, and scalable.
3. Conducting real-world evaluations to inform the design of personal health informatics tools.
4. Exploring how AI/ML can extract patterns from health data to provide meaningful insights.
5. Integrating diverse data sources (e.g., EHRs, wearables) for comprehensive health assessments.

Eligibility Requirements
Eligible applicants include higher education institutions (public or private), nonprofits, for-profit organizations (including small businesses), local/state governments, tribal governments, and foreign organizations. Individuals from diverse backgrounds are encouraged to apply.

Period of Performance
The project period may extend up to 4 years based on the scope of the proposed project.

Grant Value
Application budgets are expected to be no more than $250,000 per year in direct costs. The total value of grants will depend on NIH appropriations and the number of meritorious applications received.