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ORACLE 3C: Chronic Conditions, Coinfections, and Comorbidities in HIV

ID: PAR-26-105 • Type: Forecasted
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Description

NICHD will advance its mission by using the DP2 mechanism to support early-career investigators conducting pioneering research on HIV-related chronic conditions, coinfections, and comorbidities (3C). Scientific directions will be distinct from concepts and approaches already pursued and consistent with the scientific priorities of the Office of AIDS Research (OAR). HIV-related 3Cs cause significant and different pathology in people with and without HIV. Development of preventive and therapeutic strategies based on understanding HIV-specific pathways and mechanisms, and implementing those strategies is critical, especially in pediatric and maternal populations. All pediatric and maternal populations will be appropriate for study as the focus is on HIV prevention and/or treatment research. A pipeline of innovative researchers from other fields of research including mathematics, engineering, computer science, and AI will bring new ideas and innovative approaches. This NOFO will advance research on an important public health problem by supporting transformative research on HIV 3Cs by investigators in the early stages of an independent career.

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Overview

Agency
National Institutes of Health (NIH) [HHS]
Category of Funding
Health
Funding Instruments
Grant
Grant Program (CFDA)
93.865 - Child Health and Human Development Extramural Research
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
Grants.gov
On 2/6/26 the National Institutes of Health forecasted grant opportunity PAR-26-105 for ORACLE 3C: Chronic Conditions, Coinfections, and Comorbidities in HIV with funding of $2.0 million. The grant will be issued under grant program 93.865 Child Health and Human Development Extramural Research. It is expected that 4 total grants will be made.

Timing

Forecast Posted Date
Feb. 6, 2026, 12:00 a.m. EST
Est. Application Posting Date
July 24, 2026, 12:00 a.m. EDT
Est. Synopsis Response Date
Sept. 25, 2026, 12:00 a.m. EDT Forecasted
Last Updated
Feb. 6, 2026, 1:37 p.m. EST
Version
1

Eligibility

Eligible Applicants
Public and State controlled institutions of higher education
Public housing authorities/Indian housing authorities
Private institutions of higher education
County governments
Independent school districts
Native American tribal organizations (other than Federally recognized tribal governments)
Native American tribal governments (Federally recognized)
For profit organizations other than small businesses
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Small businesses
City or township governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
Special district governments
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Info
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Award Sizing

Ceiling
Not Listed
Floor
Not Listed
Estimated Program Funding
$1,960,000
Estimated Number of Grants
4

Contacts

Contact
NICHD MPIDB
Contact Email
nichd_mpidb_opportunities@mail.nih.gov   Profile

Documents

Posted documents for PAR-26-105

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