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Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required)

ID: RFA-MH-27-140 • Type: Posted
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Description

Posted: May 28, 2026, 12:00 a.m. EDT
NIMH seeks applications for pilot research to adapt, optimize, and test behavioral interventions that address common sleep problems in adolescents and young adults with or at risk for a mental health disorder. This notice of funding opportunity (NOFO) supports pilot clinical trials designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach in real world settings. Applications should aim to conduct a preliminary test of the intervention's impact on sleep and mental health outcomes, as well as an examination of the mechanisms that underlie the intervention's effectiveness, and to obtain preliminary data needed as a prerequisite for larger-scale effectiveness trials. In addition, interdisciplinary, collaborative teams of investigators from the fields of mental health, sleep medicine, developmental science, clinical trials research methods, behavioral economics, implementation science, data science, and human computer interaction are encouraged.
Posted: May 28, 2026, 12:00 a.m. EDT
Posted: May 28, 2025, 12:00 a.m. EDT
Posted: May 28, 2025, 12:00 a.m. EDT
Posted: May 28, 2025, 12:00 a.m. EDT
Posted: May 28, 2025, 12:00 a.m. EDT

Overview

Category of Funding
Health
Funding Instruments
Grant
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 5/28/26 the National Institutes of Health posted grant opportunity RFA-MH-27-140 for Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required) with funding of $1.5 million. The grant will be issued under grant program 93.242 Mental Health Research Grants. It is expected that 6 total grants will be made.

Timing

Posted Date
May 28, 2026, 12:00 a.m. EDT
Closing Date
Oct. 22, 2026, 12:00 a.m. EDT Due in 136 Days
Last Updated
June 1, 2026, 1:56 p.m. EDT
Version
2
Archive Date
Dec. 21, 2026

Eligibility

Eligible Applicants
Special district governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
City or township governments
State governments
County governments
Native American tribal organizations (other than Federally recognized tribal governments)
Independent school districts
Private institutions of higher education
Public and State controlled institutions of higher education
For profit organizations other than small businesses
Native American tribal governments (Federally recognized)
Small businesses
Public housing authorities/Indian housing authorities
Additional Info
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Award Sizing

Ceiling
Not Listed
Floor
Not Listed
Estimated Program Funding
$1,500,000
Estimated Number of Grants
6

Contacts

Contact
National Institutes of Health
Contact Phone
(301) 402-2541

Documents

Posted documents for RFA-MH-27-140

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