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Notice of Intent to Publish a Funding Opportunity Announcement for Trailblazer Award for New and Early-Stage Investigators (R21 Clinical Trial Optional)

ID: FOR-EB-26-001 • Type: Forecasted
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Description

The National Institute of Biomedical Imaging and Bioengineering, with the National Eye Institute, the National Institute on Aging, the National Cancer Institute, and the National Center for Complementary and Integrative Health intend to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the Trailblazer Award. This is an opportunity for NIH-defined New and Early Stage Investigators (https://grants.nih.gov/policy/early-investigators/index.htm) to pursue research programs that integrate engineering and the physical sciences with the life and/or biomedical sciences. A Trailblazer project may be exploratory, developmental, proof of concept, or high-risk high-impact, and may be technology design-directed, discovery-driven, or hypothesis-driven. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R21 activity code. Investigators with expertise and insights into the application of principles and techniques from engineering and quantitative sciences, such as physics, mathematics, chemistry, and computer sciences are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in trans-disciplinary research approaches with the potential to open new areas of biomedical investigation will be encouraged and these investigators should also begin considering applying for this application.

Overview

Category of Funding
Health
Funding Instruments
Grant
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 6/11/25 the National Institutes of Health forecasted grant opportunity FOR-EB-26-001 for Notice of Intent to Publish a Funding Opportunity Announcement for Trailblazer Award for New and Early-Stage Investigators (R21 Clinical Trial Optional). The grant will be issued under grant program 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health.

Timing

Forecast Posted Date
June 11, 2025, 12:00 a.m. EDT
Est. Application Posting Date
Nov. 21, 2025, 12:00 a.m. EST
Est. Synopsis Response Date
Feb. 16, 2026, 12:00 a.m. EST Forecasted
Last Updated
June 11, 2025, 4:17 p.m. EDT
Version
1

Eligibility

Eligible Applicants
Private institutions of higher education
County governments
Independent school districts
Public and State controlled institutions of higher education
State governments
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal governments (Federally recognized)
Small businesses
For profit organizations other than small businesses

Contacts

Contact
Randy King National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Contact Email

Documents

Posted documents for FOR-EB-26-001

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