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NIH StrokeNet- Regional Coordinating Stroke Centers for year 2023 (U24 - Clinical Trials Not Allowed)

ID: RFA-NS-23-010 • Type: Posted
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Description

The purpose of this funding opportunity announcement (FOA), issued by NINDS, is to invite currently awarded NIH StrokeNet centers and potential new stroke centers to participate as a Regional Coordinating Stroke Center (RCC) in the NIH StrokeNet clinical trials network. Established by NINDS in 2013, the goal of the NIH StrokeNet is to harness the leadership and experience of the stroke research field to maximize efficiencies for developing, promoting and conducting high-quality, multi-site clinical trials focused on promising interventions for stroke prevention, treatment, and recovery with the objective of having a balanced portfolio between all three approaches. Multi-site exploratory and confirmatory Phase 3 clinical trials as well as biomarker-validation studies that are immediately preparatory to trials and ancillary studies designed to add scientific aims to active studies will be coordinated through separate National Coordinating (NCC) and National Data Management Centers (NDMC). Funded RCC's in the network will be regional academic medical centers that include geographically or organizationally linked partners, clinical performance sites or satellite stroke centers that are committed to randomizing patients in NINDS-funded NIH StrokeNet clinical studies. RCC's will have both clinical science excellence and specialized expertise in stroke management, as well as a strong background in stroke research, and a proven ability to recruit stroke patients. Each RCC will also have strong collaborative relationships between vascular neurology, emergency medicine, interventional neuroradiology, neurosurgery, neurointensive care, neuroimaging, stroke rehabilitation, and pediatric neurology, thereby demonstating a commitment to offer all eligible patients the opportunity to participate in a trial conducted through the network. In addition, the NIH Stroke Trials Network will include an active stroke research career advancement program.
Background
The National Institute of Neurological Disorders and Stroke (NINDS) is inviting currently awarded NIH StrokeNet centers and potential new stroke centers to participate as a Regional Coordinating Stroke Center (RCC) in the NIH StrokeNet clinical trials network. The goal of the NIH StrokeNet is to harness the leadership and experience of the stroke research field to maximize efficiencies for developing, promoting, and conducting high-quality, multi-site clinical trials focused on promising interventions for stroke prevention, treatment, and recovery.

Grant Details
Funded RCC's in the network will be regional academic medical centers that include geographically or organizationally linked partners, clinical performance sites or satellite stroke centers that are committed to randomizing patients in NINDS-funded NIH StrokeNet clinical studies. RCCs will have both clinical science excellence and specialized expertise in stroke management, as well as a strong background in stroke research, and a proven ability to recruit stroke patients. Each RCC will also have strong collaborative relationships between vascular neurology, emergency medicine, interventional neuroradiology, neurosurgery, neurointensive care, neuroimaging, stroke rehabilitation, and pediatric neurology. The NIH Stroke Trials Network will include an active stroke research career advancement program.

Eligibility Requirements
The eligible applicants include higher education institutions, nonprofits with 501(c)(3) IRS status, for-profit organizations (including small businesses), local governments, state governments, county governments, city or township governments, special district governments, Indian/Native American tribal governments (both federally recognized and other than federally recognized), federal government agencies or U.S. territories or possessions. Foreign institutions are not eligible to apply.

Period of Performance
The project period is limited to 5 years with an earliest start date of February 28, 2023 and an expiration date of March 01, 2023.

Grant Value
NINDS intends to commit $11,500,000 in FY 2023 to fund up to 27 awards. The maximum allowable direct cost per year for a NIH StrokeNet RCC will be $275,000.
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Overview

Agency
National Institutes of Health (NIH) [HHS]
Category of Funding
Health
Funding Instruments
Cooperative Agreement
Grant Program (CFDA)
93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
Grants.gov
On 12/15/22 the National Institutes of Health posted grant opportunity RFA-NS-23-010 for NIH StrokeNet- Regional Coordinating Stroke Centers for year 2023 (U24 - Clinical Trials Not Allowed). The grant will be issued under grant program 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.

Timing

Posted Date
Dec. 15, 2022, 12:00 a.m. EST
Closing Date
Feb. 28, 2023, 12:00 a.m. EST Past Due
Last Updated
Dec. 15, 2022, 11:52 a.m. EST
Version
1
Archive Date
April 5, 2023

Eligibility

Eligible Applicants
For profit organizations other than small businesses
Public and State controlled institutions of higher education
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Special district governments
County governments
Small businesses
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Public housing authorities/Indian housing authorities
State governments
Private institutions of higher education
City or township governments
Native American tribal governments (Federally recognized)
Native American tribal organizations (other than Federally recognized tribal governments)
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Independent school districts
Additional Info
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Award Sizing

Ceiling
$1,750,000
Floor
Not Listed
Estimated Program Funding
Not Provided
Estimated Number of Grants
Not Listed

Contacts

Contact
National Institutes of Health
Contact Email
grantsinfo@nih.gov
Email Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Contact Phone
(301) 402-2541
Additional Information
https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-23-010.html
Additional Information Site
http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-23-010.html

Documents

Posted documents for RFA-NS-23-010

Grant Awards

Grants awarded through RFA-NS-23-010

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