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NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)

ID: PA-25-306 • Type: Posted
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Description

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This Parent Notice of Funding Opportunity requires that at least 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.Applicants should note that some ICs (see Related Notices) only accept applications proposing mechanistic studies that meet NIH's definition of a clinical trial through this funding opportunity announcement.
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Overview

Agency
National Institutes of Health (NIH) [HHS]
Category of Funding
Education
Environment
Health
Income Security and Social Services
Funding Instruments
Grant
Grant Program (CFDA)
93.113 - Environmental Health
93.143 - NIEHS Superfund Hazardous Substances Basic Research and Education
93.172 - Human Genome Research
93.173 - Research Related to Deafness and Communication Disorders
93.213 - Research and Training in Complementary and Integrative Health
93.233 - National Center on Sleep Disorders Research
93.242 - Mental Health Research Grants
93.273 - Alcohol Research Programs
93.279 - Drug Abuse and Addiction Research Programs
93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health
93.307 - Minority Health and Health Disparities Research
93.361 - Nursing Research
93.393 - Cancer Cause and Prevention Research
93.394 - Cancer Detection and Diagnosis Research
93.395 - Cancer Treatment Research
93.396 - Cancer Biology Research
93.399 - Cancer Control
93.837 - Cardiovascular Diseases Research
93.838 - Lung Diseases Research
93.839 - Blood Diseases and Resources Research
93.840 - Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
93.846 - Arthritis, Musculoskeletal and Skin Diseases Research
93.855 - Allergy and Infectious Diseases Research
93.865 - Child Health and Human Development Extramural Research
93.866 - Aging Research
93.867 - Vision Research
93.879 - Medical Library Assistance
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
Grants.gov
On 12/18/24 the National Institutes of Health posted grant opportunity PA-25-306 for NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required). The grant will be issued under grant program 93.113 Environmental Health.

Timing

Posted Date
Dec. 18, 2024, 12:00 a.m. EST
Closing Date
Jan. 7, 2028, 12:00 a.m. EST Due in 817 Days
Last Updated
Sept. 4, 2025, 2:04 p.m. EDT
Version
5
Archive Date
Feb. 12, 2028

Eligibility

Eligible Applicants
Small businesses
Private institutions of higher education
County governments
City or township governments
State governments
Public housing authorities/Indian housing authorities
For profit organizations other than small businesses
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Special district governments
Native American tribal governments (Federally recognized)
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Independent school districts
Public and State controlled institutions of higher education
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
Additional Info
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Contacts

Contact
National Institutes of Health
Contact Email
grantsinfo@nih.gov
Email Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Contact Phone
(301) 402-2541
Additional Information
https://grants.nih.gov/grants/guide/pa-files/PA-25-306.html
Additional Information Site
http://grants.nih.gov/grants/guide/pa-files/PA-25-306.html

Documents

Posted documents for PA-25-306

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