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NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional)

ID: PA-26-002 • Type: Posted
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Description

Posted: Jan. 20, 2026, 12:00 a.m. EST
The National Institutes of Health (NIH) seeks to advance its mission by maintaining strong, productive, and secure international research collaborations in support of the NIH mission. The NIH Collaborative International Research Project (Parent Announcement) supports international research collaborations. This opportunity specifically implements an award structure of prime domestic awards with independent foreign awards that are linked to the prime. This structure provides NIH with oversight capacity for international collaborations, and allows NIH to track international funding, as identified in NOT-OD-25-104. This funding opportunity is specifically designed for NIH to support funded international collaborations between a domestic prime organization and foreign organizations. This NOFO should not be used for foreign consultants, purchasing unique equipment or supplies from foreign vendors, foreign collaborations that do not involve NIH funding or any other foreign component that would not result in a foreign subaward. All collaborative international research project applications must include at least 1 international subproject. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes, Centers and Offices (ICOs) based on their scientific missions. The application will be evaluated as a whole, and the international subproject(s) will be evaluated on whether the project presents special opportunities for furthering research programs through the use of unusual talent, resources, populations, or environmental conditions in other countries that are not readily available in the United States or that augment existing United States resources, and whether the proposed project has specific relevance to the mission and objectives of the ICO and has the potential for significantly advancing the health sciences in the United States.
Posted: Sept. 15, 2025, 12:00 a.m. EDT
Posted: Sept. 15, 2025, 12:00 a.m. EDT
Background
The National Institutes of Health (NIH) aims to enhance health and reduce illness through strong international research collaborations.

The NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional) is designed to support funded international collaborations between a domestic prime organization and foreign organizations, ensuring NIH oversight and tracking of international funding.

Grant Details
This funding opportunity supports collaborative projects structured as prime domestic awards with linked independent foreign awards.

Each application must include at least one international subproject related to the scientific missions of participating NIH Institutes, Centers, and Offices (ICOs). Applications will be evaluated based on their potential to leverage unique resources or populations not available in the U.S. and their relevance to the ICO's mission.

The application must include components such as Overall, Research Project, and International Project, detailing goals, significance, innovation, approach, and scope of work for both domestic and international efforts.

Eligibility Requirements
Eligible applicants include higher education institutions (public and private), nonprofits, for-profit organizations (including small businesses), local/state governments, tribal governments, and other entities.

Foreign organizations are not eligible to apply directly but can participate as collaborators. Each application must have at least one international project component.

Period of Performance
The project period is determined by the scope of the proposed project, generally up to 5 years for non-clinical trials and up to 7 years for clinical trials.

Grant Value
The total value of the grant is contingent upon NIH appropriations; there is no specified limit on application budgets but they should reflect actual project needs.

Place of Performance
The grant will be performed in both domestic locations within the United States and in foreign countries where collaborating organizations are based.
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Overview

Agency
National Institutes of Health (NIH) [HHS]
Category of Funding
Health
Funding Instruments
Grant
Grant Program (CFDA)
93.310 - Trans-NIH Research Support
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
Grants.gov
On 1/20/26 the National Institutes of Health posted grant opportunity PA-26-002 for NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional). The grant will be issued under grant program 93.310 Trans-NIH Research Support.

Timing

Posted Date
Jan. 20, 2026, 12:00 a.m. EST
Closing Date
May 7, 2029, 12:00 a.m. EDT Due in 1150 Days
Last Updated
Jan. 20, 2026, 6:36 p.m. EST
Version
1
Archive Date
July 9, 2029

Eligibility

Eligible Applicants
County governments
Special district governments
City or township governments
Native American tribal organizations (other than Federally recognized tribal governments)
Private institutions of higher education
For profit organizations other than small businesses
Public housing authorities/Indian housing authorities
Small businesses
Public and State controlled institutions of higher education
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Independent school districts
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Native American tribal governments (Federally recognized)
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
Additional Info
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.One or more International Project is required.This funding opportunity is specifically designed to support funded international collaborations between a domestic prime organization and foreign organizations. This NOFO should not be used for projects in which the only international elements are foreign consultants, purchasing unique equipment or supplies from foreign vendors, foreign collaborations that do not involve NIH funding or any other foreign component that would not result in a foreign subaward.

Contacts

Contact
National Institutes of Health
Contact Email
operasystemspolicy@mail.nih.gov
Contact Phone
(301) 402-2541

Documents

Posted documents for PA-26-002

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