Search Grant Opportunities

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)

ID: PAR-24-172 • Type: Posted


The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. The proposed trial can be single or multisite. Applicants applying for funding under this NOFO should be ready to initiate the clinical trial within the first quarter of the project period. Discussion, submission, and attainment of applicable regulatory (FDA, DSMB, IRB) approvals, and establishment of drug (and placebo, if applicable) supplies, and any necessary third-party agreements should be established by the time of award. If time and support for these and other pre-clinical and/or trial readiness activities are desired, applicants should consider the companion NOFO which utilizes an R61/R33 phased approach.


Category of Funding
Funding Instruments
Grant Category
Cost Sharing / Matching Requirement
On 4/1/24 the National Institutes of Health posted grant opportunity PAR-24-172 for NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required). The grant will be issued under grant program 93.233 National Center on Sleep Disorders Research.


Posted Date
April 1, 2024, 12:00 a.m. EDT
Closing Date
Jan. 7, 2027, 12:00 a.m. EST Due in 992 Days
Last Updated
April 1, 2024, 4:28 p.m. EDT
Archive Date
Feb. 12, 2027


Eligible Applicants
Others (see text field entitled "Additional Information on Eligibility" for clarification)
State governments
Small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
Public and State controlled institutions of higher education
Private institutions of higher education
Independent school districts
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Special district governments
For profit organizations other than small businesses
County governments
Public housing authorities/Indian housing authorities
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
City or township governments
Native American tribal governments (Federally recognized)
Additional Info
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Award Sizing

Not Listed
Estimated Program Funding
Not Provided
Estimated Number of Grants
Not Listed


National Institutes of Health
Contact Email
Email Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Contact Phone
(301) 402-2541
Additional Information


Posted documents for PAR-24-172

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