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NextTech: Translational Development of Next-Generation Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)

ID: RFA-EB-26-004 • Type: Forecasted
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Description

This Notice of Funding Opportunity (NOFO) is to encourage applications from investigators to advance the development and translation of next-generation technologies to prevent, monitor, diagnose, and treat disorders within the missions of the NIH Brain Research through Advancing Innovative Neurotechnologies (BRAIN) and The Helping to End Addiction Long-term (HEAL) Initiatives. Awarded activities will facilitate the translation of new devices up to the stage of readiness for first in human (FIH) clinical trials by overcoming key challenges identified during preliminary proof-of-concept studies. The scope of the program includes technology development and optimization, and studies to prepare for approvals for human use.

Overview

Category of Funding
Health
Funding Instruments
Grant
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 2/27/26 the National Institutes of Health forecasted grant opportunity RFA-EB-26-004 for NextTech: Translational Development of Next-Generation Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed) with funding of $6.0 million. The grant will be issued under grant program 93.121 Oral Diseases and Disorders Research. It is expected that 4 total grants will be made.

Timing

Forecast Posted Date
Feb. 27, 2026, 12:00 a.m. EST
Est. Application Posting Date
July 17, 2026, 12:00 a.m. EDT
Est. Synopsis Response Date
Sept. 18, 2026, 12:00 a.m. EDT Forecasted
Last Updated
Feb. 27, 2026, 10:50 a.m. EST
Version
1

Eligibility

Eligible Applicants
Independent school districts
State governments
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Small businesses
For profit organizations other than small businesses
County governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
City or township governments
Native American tribal governments (Federally recognized)
Special district governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Public and State controlled institutions of higher education
Additional Info
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Award Sizing

Ceiling
Not Listed
Floor
Not Listed
Estimated Program Funding
$6,000,000
Estimated Number of Grants
4

Contacts

Contact
NIBIB Program Officers for RFA-EB-26-004

Documents

Posted documents for RFA-EB-26-004

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