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NCI Clinical and Translational Exploratory/Developmental Studies (R21 Clinical Trial Optional)

ID: PAR-25-139 • Type: Posted
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Description

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to supports the development of new exploratory research in cancer diagnosis, treatment, imaging, symptom/toxicity, and prevention clinical trials; correlative studies associated with clinical trials; novel cancer therapeutic, symptom/toxicity, and preventive agent development, radiotherapy development activities, and mechanism-driven combinations; and innovative preclinical studies--including the use of new clinically-relevant models and imaging technologies--which could lead to first-in-human clinical trials. The R21 mechanism is intended to encourage exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of cancer research (pre-clinical or clinical).

Overview

Category of Funding
Education
Health
Funding Instruments
Grant
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 11/4/24 the National Institutes of Health posted grant opportunity PAR-25-139 for NCI Clinical and Translational Exploratory/Developmental Studies (R21 Clinical Trial Optional) with funding of $200,000. The grant will be issued under grant program 93.393 Cancer Cause and Prevention Research.

Timing

Posted Date
Nov. 4, 2024, 12:00 a.m. EST
Closing Date
Sept. 7, 2025, 12:00 a.m. EDT Past Due
Last Updated
May 14, 2025, 12:18 p.m. EDT
Version
2
Archive Date
Oct. 7, 2025

Eligibility

Eligible Applicants
Special district governments
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Independent school districts
Public and State controlled institutions of higher education
Private institutions of higher education
State governments
City or township governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
For profit organizations other than small businesses
Small businesses
County governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Additional Info
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Award Sizing

Ceiling
$275,000
Floor
Not Listed
Estimated Program Funding
$200,000
Estimated Number of Grants
Not Listed

Contacts

Contact
National Institutes of Health
Contact Email
Email Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Contact Phone
(301) 402-2541
Additional Information
https://grants.nih.gov/grants/guide/pa-files/PAR-25-139.html

Documents

Posted documents for PAR-25-139

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