Lung Transplant Consortium - Data Coordinating Center (U24 - Clinical Trial Not Allowed)

This Funding Opportunity Announcement (FOA) invites applications to serve as the Data Coordinating Center (DCC) that will support the activities of the Lung Transplant Consortium (LTC). The primary responsibility of the DCC will be to oversee the conduct of multiple observational clinical studies involving lung transplantation in the LTC. The DCC will support regulatory and administrative activities, data and biospecimen collection and management, statistical analyses, and the reporting of study results in a timely manner. The DCC will promote collaboration and communication among LTC investigators and the broader research community and will coordinate outreach activities including engaging foundations, societies, and other entities with a shared interest in lung transplantation. The DCC will be responsible for integrating the efforts of approximately 24 individual LTC Clinical Centers performing observational research studies to identify factors that impact donor lung utilization and the development of acute lung allograft dysfunction in lung transplant recipients. The NHLBI anticipates that the DCC will collaborate strategically with the LTC Clinical Centers to provide support for protocol development, statistical data analyses, biospecimen collection and storage, the publication of results, and providing datasets for secondary analyses by the broader research community. This FOA runs in parallel with a separate FOA that invites applications for the LTC Clinical Centers, described in detail in RFA-HL-22-002