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Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (Clinical Trial Optional)

ID: PAR-26-123 • Type: Forecasted
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Description

The purpose of this NOFO is to enhance the capability of NCATS CTSA Program KL2 scholars supported by the CTSA Program to conduct research as they complete the transition to fully independent academic translational scientists. These small research grants will support different clinical and translational science research projects, including pilot and feasibility studies; secondary data analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. Research proposed in the application may or may not include patient-oriented research. This small research grant is, therefore, intended to support research projects that can be carried out in a short period of time with limited resources and that provide preliminary data to support submission of a subsequent research project grant, or equivalent, application.

Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Background
The National Center for Advancing Translational Sciences (NCATS) is issuing this Notice of Funding Opportunity (NOFO) to enhance the capabilities of NCATS Clinical and Translational Science Award (CTSA) Program KL2 scholars. The goal is to support their transition to fully independent academic translational scientists through small research grants aimed at various clinical and translational science research projects.

Grant Details
This grant will support a range of clinical and translational science research projects, including: pilot and feasibility studies; secondary data analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. The proposed research may or may not include patient-oriented research. The grants are intended for projects that can be completed in a short timeframe with limited resources, providing preliminary data for subsequent larger grant applications. Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

Eligibility Requirements
Eligible organizations must meet specific criteria outlined in the Eligibility Section of the NOFO. Applications will undergo NIH standard peer-review processes, with only meritorious applications considered for funding.

Period of Performance
The period of performance is implied to be short-term to align with the nature of the small research projects supported by this grant.

Grant Value
The total value of the grant opportunity is not specified in the provided text.
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Overview

Agency
National Institutes of Health (NIH) [HHS]
Category of Funding
Health
Funding Instruments
Grant
Grant Program (CFDA)
93.350 - National Center for Advancing Translational Sciences
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
Grants.gov
On 2/18/26 the National Institutes of Health forecasted grant opportunity PAR-26-123 for Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (Clinical Trial Optional). The grant will be issued under grant program 93.350 National Center for Advancing Translational Sciences.

Timing

Forecast Posted Date
Feb. 18, 2026, 12:00 a.m. EST
Est. Application Posting Date
Aug. 17, 2026, 12:00 a.m. EDT
Est. Synopsis Response Date
Oct. 17, 2026, 12:00 a.m. EDT Forecasted
Last Updated
Feb. 18, 2026, 12:37 p.m. EST
Version
1

Eligibility

Eligible Applicants
County governments
Special district governments
Public and State controlled institutions of higher education
Public housing authorities/Indian housing authorities
City or township governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Independent school districts
State governments
For profit organizations other than small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
Private institutions of higher education
Small businesses
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal governments (Federally recognized)
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Info
Eligibility is limited to NCATS CTSA Program supported scholars who received direct NCATS funding from the NCATS CTSA Program Institutional Career Development Core/Program (KL2/K12) and completed the KL2/K12 training program. The date of submission deadline must be within two years of completion of their NIH appointment. Eligibility for resubmissions will be extended for 12 months past the first submission.Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations

Contacts

Contact
NCATS CTSA Program Branch
Contact Email
ctsa_r03_nofo_questions@nih.gov
Email Description
CTSA Program Branch, Division of Clinical Innovation, NCATS

Documents

Posted documents for PAR-26-123

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