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Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)

ID: RFA-HL-25-011 • Type: Posted

Description

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit current or recently completed NHLBI K01, K08, K23, and K25 awardees for small grant support to expand their current research objectives or to branch out to a new study that resulted from the research conducted under the K award. Active NHLBI K01, K08, K23, and K25 awardees may apply for R03 support after the notices of award (NoA) for their first type-5 K awards have been issued. Recently completed NHLBI K01, K08, K23, and K25 awardees are eligible to apply for the R03 if the earliest possible R03 start date falls within 2 years of their prior NHLBI K award Project Period end date. This FOA is intended to enhance the capability of NHLBI K01, K08, K23, and K25 awardees to conduct research as they complete their transition to fully independent investigator status. This R03 grant mechanism is intended to support research projects that can be carried out and completed within a short period of time (no more than two years) with limited resources and that may generate preliminary data to support a subsequent R01-equivalent application. These studies include, but not limited to, pilot or feasibility studies; proof of concept studies; secondary analysis of existing data; small, self-contained research projects; development of new research methodologies or technologies, or development of novel experimental models. For current and previous K23 awardees, research proposed in the R03 application may or may not include patient-oriented research. A minimum of 40% protected overall research effort is required from applicants during the R03 award period and can be met through a combination of effort on the proposed R03 and other research projects, regardless of funding source.
Background
The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) is issuing this Notice of Funding Opportunity (NOFO) to support current or recently completed NHLBI K01, K08, K23, and K25 awardees. The goal is to provide small grant support to enhance their research capabilities as they transition to independent investigator status. This funding opportunity aims to facilitate the expansion of existing research objectives or the initiation of new studies stemming from prior K award research.

Grant Details
This R03 grant mechanism supports research projects that can be completed within a short timeframe (no more than two years) and with limited resources. Eligible studies may include pilot or feasibility studies, proof of concept studies, secondary analysis of existing data, small self-contained research projects, development of new methodologies or technologies, and novel experimental models. A minimum of 40% protected overall research effort is required from applicants during the R03 award period. This effort can be met through a combination of work on the proposed R03 project and other research projects.

Eligibility Requirements
Eligible applicants include current NHLBI-supported K01, K08, K23, and K25 recipients who may apply for R03 support after receiving a notice of award for their first type-5 K award. Recently completed NHLBI K recipients are also eligible if their earliest possible R03 start date falls within two years following their prior NHLBI K award project period end date. Individuals from diverse backgrounds are encouraged to apply.

Period of Performance
The maximum project period for the R03 grant is two years.

Grant Value
NHLBI intends to commit total costs up to $2.4 million in FY2024, $4.8 million in FY2025, $4.8 million in FY2026, and $2.4 million in FY2027 for this program. Application budgets are limited to direct costs up to $75,000 per year.

Overview

On 12/16/24 the National Institutes of Health posted grant opportunity RFA-HL-25-011 for Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional) with funding of $75,000. The grant will be issued under grant program 93.233 National Center on Sleep Disorders Research.

Timing

Posted Date
Dec. 16, 2024, 12:00 a.m. EST
Closing Date
Jan. 7, 2026, 12:00 a.m. EST Due in 334 Days
Last Updated
Dec. 16, 2024, 12:22 p.m. EST
Version
1
Archive Date
Feb. 12, 2026

Eligibility

Eligible Applicants
Small businesses
City or township governments
Native American tribal governments (Federally recognized)
Public and State controlled institutions of higher education
Public housing authorities/Indian housing authorities
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Private institutions of higher education
For profit organizations other than small businesses
Independent school districts
State governments
County governments
Special district governments
Additional Info
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Award Sizing

Ceiling
$75,000
Floor
Not Listed
Estimated Program Funding
$75,000
Estimated Number of Grants
Not Listed

Contacts

Contact
National Institutes of Health
Contact Email
Email Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Contact Phone
(301) 402-2541
Additional Information
https://grants.nih.gov/grants/guide/rfa-files/RFA-HL-25-011.html

Documents

Posted documents for RFA-HL-25-011

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