Limited Competition: Nonhuman Primate (NHP) Radiation Survivor Cohort (RSC) (U01 Clinical Trial Not Allowed)

The purpose of this limited competition Funding Opportunity Announcement (FOA) is to support continued care for and conduct of specialized research using a unique nonhuman primate (NHP) population. Specifically, the preservation, medical monitoring, study, treatment, and intervention in the development of late effects in NHP survivors of radiation exposure. NHPs most closely resemble human responses to radiation exposure and, as such, long-term studies on a radiation survivor cohort will permit continuous observations and treatment of this valuable population, while providing a critical understanding of the natural history of radiation exposures, including early and late injuries and disease development. The successful applicant must have facilities and staff to care for a combined minimum of 120 irradiated and unirradiated control NHPs, exposed at various ages and available for study, and must be able to accommodate receipt of additional radiation-exposed animals from other government-supported studies.