Limited Competition: NIDDK Program Projects (P01 Clinical Trial Optional)

Background
The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is offering a limited competition grant opportunity for investigator-initiated Research Program Project Grant (P01) renewal (Type 2) applications. The P01 program project award supports research that has multiple distinct but synergistic projects built around a unifying central theme within the scientific mission of the NIDDK. The program aims to foster multi-disciplinary, collaborative research projects and requires a central theme or well-defined major objective as the foundation of the project.

Grant Details
The grant supports research that advances the mission of NIDDK to gain new knowledge relevant to understanding diabetes, selected endocrine and metabolic diseases, and to develop new approaches to prevent, treat, and cure these diseases. The program project requires a minimum of three inter-related and synergistic research projects that complement and contribute to a unifying central theme, at least one research core facility that provides services to at least two research projects, and an administrative support core may also be proposed. The project leaders and core leaders should be established investigators with strong records of innovative research and independent funding support.

Eligibility Requirements
Eligible applicants include higher education institutions, nonprofits, for-profit organizations, state governments, county governments, city or township governments, special district governments, Indian/Native American Tribal Governments (Federally Recognized), eligible agencies of the Federal Government, U.S. Territory or Possession. Foreign Institutions are not eligible to apply. Only current NIDDK-supported P01 awardees who are in the first project period (i.e., first five years of funding) are eligible to submit a renewal (Type 2) application via this funding opportunity.

Period of Performance
The maximum project period for these awards is 5 years.

Grant Value
Applications should not request more than $6.25 million in direct costs over 5 years. The number of awards is contingent upon the NIDDK budget and the number of highly meritorious applications.