Search Grant Opportunities

Limited Competition: Molecular Transducers of Physical Activity Chemical Analysis Sites (U24 Clinical Trial Not Allowed)

ID: RFA-RM-23-021 • Type: Posted
Opportunity Assistant

Hello! Please let me know your questions about this opportunity. I will answer based on the available opportunity documents.

Sign in to upload a capability statement or catalogue for your company

Some suggestions:
Please summarize the work to be completed under this opportunity
Who is eligible to apply for this grant?
I'd like to anonymously submit a question to the procurement officer(s)

Description

The purpose of this FOA is to invite applications for Chemical Analysis Sites to serve as part of the Molecular Transducers of Physical Activity Consortium (MoTrPAC; http://commonfund.nih.gov/MolecularTransducers). This is a limited competition FOA and open only to the previously funded grantees of MoTrPAC Chemical Analysis sites through RFA-RM-15-010 and RFA-RM-15-011. Awards made through this FOA will support participation of grantees in the MoTrPAC consortium activities and the continuation of the analysis of tissues collected by the MoTrPAC consortium. Awardees will conduct omics analysis of tissues collected from human participants undergoing a physical activity intervention, generate well curated datasets, contribute that data to a public consortium database, and participate in the data analysis to generate molecular fingerprints of candidate transducers of physical activity.
Background
The purpose of this FOA is to invite applications for Chemical Analysis Sites to serve as part of the Molecular Transducers of Physical Activity Consortium (MoTrPAC). MoTrPAC is a national research consortium designed to discover and perform preliminary characterization of the range of molecular transducers that underlie the effects of physical activity. The overall goal is to understand the biological processes and pathways through which physical activity influences health and disease outcomes.
MoTrPAC seeks to create a map of the molecular changes that occur after physical activity, in animal models and in humans, and place this information into a user-friendly database accessible to the larger research community.

Grant Details
The Chemical Analysis Sites (CAS) will conduct omics analysis of tissues collected from human participants undergoing a physical activity intervention, generate well curated datasets, contribute that data to a public consortium database, and participate in the data analysis to generate molecular fingerprints of candidate transducers of physical activity.
The CAS will work with the Steering Committee to plan, execute and complete the clinical study; propose a plan for tissue analysis of human samples, contribute to and complete the data analysis from preclinical animal studies, advise and facilitate appropriate sample handling and preparation strategies for all assays at the Clinical Centers, provide stewardship for performing appropriate assays with well validated protocols, perform initial analysis of datasets including data QA/QC and other necessary data curation, ensure timely delivery of all data in formats compliant with the data standards agreed by the consortium, contribute to overall consortium activities and comply with the consortium policies and procedures.

Eligibility Requirements
This is a limited competition open only to currently supported Molecular Transducers of Physical Activity Consortium (MoTrPAC) Chemical Analysis Sites (CAS).
The MoTrPAC Chemical Analysis Sites (CAS) refer to sites previously awarded through NOFOs RFA-RM-15-010 and RFA-RM-15-011.
Currently, there are seven MoTrPAC CAS awards: two Genomics, Epigenomics and Transcriptomics (GET) Sites, awarded through RFA-RM-15-010; and five sites for metabolomics and proteomics analysis (P&M), awarded through RFA-RM-15-011.

Period of Performance
The period of performance may not exceed three years.

Grant Value
The NIH Common Fund intends to commit $2,900,000 in FY 2024 to fund up to seven awards.
Application budgets are limited to $350,000 direct costs.
Show All

Overview

Agency
National Institutes of Health (NIH) [HHS]
Category of Funding
Health
Funding Instruments
Cooperative Agreement
Grant Program (CFDA)
93.310 - Trans-NIH Research Support
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
Grants.gov
On 5/2/23 the National Institutes of Health posted grant opportunity RFA-RM-23-021 for Limited Competition: Molecular Transducers of Physical Activity Chemical Analysis Sites (U24 Clinical Trial Not Allowed). The grant will be issued under grant program 93.310 Trans-NIH Research Support.

Timing

Posted Date
May 2, 2023, 12:00 a.m. EDT
Closing Date
July 24, 2023, 12:00 a.m. EDT Past Due
Last Updated
May 3, 2023, 11:39 a.m. EDT
Version
1
Archive Date
Aug. 29, 2023

Eligibility

Eligible Applicants
Small businesses
Additional Info
Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. See full Notice of Funding Opportunity for additional details on eligibility.

Award Sizing

Ceiling
$350,000
Floor
Not Listed
Estimated Program Funding
Not Provided
Estimated Number of Grants
Not Listed

Contacts

Contact
National Institutes of Health
Contact Email
grantsinfo@nih.gov
Email Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Contact Phone
(301) 402-2541
Additional Information
https://grants.nih.gov/grants/guide/rfa-files/RFA-RM-23-021.html
Additional Information Site
http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-23-021.html

Documents

Posted documents for RFA-RM-23-021

Grant Awards

Grants awarded through RFA-RM-23-021

Incumbent or Similar Grants

Grants similar to RFA-RM-23-021

Similar Active Opportunities

Open grant opportunities similar to RFA-RM-23-021