Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science for UM1 CTSA Hub Awards (RC2 Clinical Trials Optional)

Background
The purpose of the High Impact Specialized Innovation Programs (SIPs) is to support the development and demonstration of unique hub capabilities, research platforms and/or resources to address in a timely manner critical gap areas and/or roadblocks in clinical and translational science at awarded UM1 Clinical and Translational Science Awards (CTSA) Program Hubs. Successful programs supported through this funding opportunity are expected to lay a strong foundation for future adoption and/or dissemination of capabilities to additional CTSA Program Hubs.

Grant Details
The High Impact Specialized Innovation Programs (SIPs) should address objectives such as groundbreaking, innovative, high impact and cross-cutting research, resources and/or activities that address one or more of the CTSA Program Goals, creation of unique resources and/or development of transformative technologies and/or platforms that can benefit a wide range of projects and/or activities related to CTS at CTSA UM1 hubs, high-impact discovery-based projects or hypothesis-generating science. The proposed project should be unique, solve a real gap or overcome a key roadblock in clinical and translational science, demonstrate outcomes that promote and advance the NCATS Strategic Plan, accelerate the development of innovative resources, approaches, tools, solutions, therapies, diagnostics, devices and/or applications, help overcome roadblocks in clinical and translational science, catalyze clinical and translational science locally at UM1 hubs, integrate into the broader clinical and translational science community locally, regionally and/or nationally.

Eligibility Requirements
All applicant organizations and/or active award recipients for PAR-21-293 Clinical and Translational Science Award (UM1 Clinical Trial Optional) are eligible to apply under this NOFO. Only the primary UM1 CTSA program hub organization is eligible to apply (not partner or collaborator institutions). RC2 companion optional applications may be submitted under specific scenarios.

Period of Performance
The requested project period may be up to 5 years. Applications are due by 5:00 PM local time of applicant organization. The earliest start date is January 12, 2024.

Grant Value
Application budgets are limited to no more than $500,000/year in direct costs excluding consortium/contractual F&A costs. The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. Funding will be contingent upon the funding of the primary CTSA UM1 hub at the time of award.