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Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Therapeutic Agent Identification

ID: PAR-26-058 • Type: Forecasted
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Description

The National Institute of Neurological Disorders and Stroke, National Institute of Aging, the NIH Helping to End Addiction Long Term (HEAL) initiative, and other participating NIH Institutes/Centers (ICs) seek to support applications to develop in vitro, ex vivo or in vivo assays and conduct screening efforts with the goal of identifying and characterizing potential therapeutic agents for disorders or diseases supported by participating ICs, or for non-opioid analgesic therapeutics with little or no addiction liability as a part of the NIH Helping to End Addiction Long Term (HEAL) initiative. Therapeutic agents include small molecules and biologics. Assays utilizing New Approach Methodologies (NAMs) may be used when appropriate.

Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

Overview

Category of Funding
Health
Funding Instruments
Grant
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 2/25/26 the National Institutes of Health forecasted grant opportunity PAR-26-058 for Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Therapeutic Agent Identification. The grant will be issued under grant program 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.

Timing

Forecast Posted Date
Feb. 25, 2026, 12:00 a.m. EST
Est. Application Posting Date
July 30, 2026, 12:00 a.m. EDT
Est. Synopsis Response Date
Sept. 30, 2026, 12:00 a.m. EDT Forecasted
Last Updated
Feb. 25, 2026, 2:48 p.m. EST
Version
1

Eligibility

Eligible Applicants
Others (see text field entitled "Additional Information on Eligibility" for clarification)
City or township governments
Independent school districts
County governments
Private institutions of higher education
State governments
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Special district governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
For profit organizations other than small businesses
Public and State controlled institutions of higher education
Small businesses
Additional Info
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Contacts

Contact
NINDS_IGNITE@nih.gov
Contact Email

Documents

Posted documents for PAR-26-058

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