Search Grant Opportunities

IND-enabling Studies of Somatic Genome Editing Therapeutic Leads (U19, Clinical Trial Not allowed)

ID: RFA-RM-22-015 • Type: Posted

Description

Posted: April 11, 2022, 12:00 a.m. EDT
This funding opportunity announcement (FOA) is part of a suite of FOAs of the NIH Common Fund Somatic Cell Genome Editing (SCGE) Phase II Program. The goal of this U19 FOA is to support team-based research Projects to accelerate further optimization and development of genome editing-based therapeutic leads towards IND-enabling studies and an IND (Investigational New Drug) application submission to the U.S. Food and Drug Administration (FDA). The proposed leads should demonstrate strong biological rationale and in vitro and/or in vivo proof of concept (POC) data generated in model system(s) each defined by the targeted cell or tissue type to establish a genome editing therapeutic approach that is potentially adaptable to target different pathogenic variants in the same cell or tissue types.
Posted: March 24, 2022, 12:00 a.m. EDT
Posted: March 24, 2022, 12:00 a.m. EDT

Overview

Category of Funding
Health
Funding Instruments
Cooperative Agreement
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 4/11/22 the National Institutes of Health posted grant opportunity RFA-RM-22-015 for IND-enabling Studies of Somatic Genome Editing Therapeutic Leads (U19, Clinical Trial Not allowed). The grant will be issued under grant program 93.310 Trans-NIH Research Support.

Timing

Posted Date
April 11, 2022, 12:00 a.m. EDT
Closing Date
July 19, 2022, 12:00 a.m. EDT Past Due
Last Updated
April 11, 2022, 12:51 p.m. EDT
Version
1
Archive Date
Aug. 24, 2022

Eligibility

Eligible Applicants
City or township governments
Public housing authorities/Indian housing authorities
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
County governments
Small businesses
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal governments (Federally recognized)
Public and State controlled institutions of higher education
Private institutions of higher education
State governments
For profit organizations other than small businesses
Special district governments
Independent school districts
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Info
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Contacts

Contact
National Institutes of Health
Email Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Contact Phone
(301) 402-2541

Documents

Posted documents for RFA-RM-22-015

Grant Awards

Grants awarded through RFA-RM-22-015

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