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Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS)

ID: RFA-TS-26-165 • Type: Forecasted
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Description

CDC/ATSDR is inviting research proposals to study risk factors for Amyotrophic Lateral Sclerosis (ALS). Studies on military service, contact sports, traumatic brain injury, neuroinflammation, and infections agents and exposures are encourages. Funding will be for four funding options: Option A - Support research with strong existing evidence such as studies on known environmental or genetic risk factors, research that improves past studies with better data, or investigations linking risk factors to ALS diagnosis and treatment; Option B - Support new and exploratory research on ALS risk factors such as studies on risk factors with little existing evidence or research using innovative methods; Option C - Understand ALS risk in affected populations, such as studies involving military veterans or investigations of ALS risk factors impacting this population; Option D - Analyze biological samples from the Guamanian ALS cluster such as investigation of disease mechanisms and environmental factors, exposure routes, genetic studies and biomarkers and how this could lead to mitigation therapeutics, diagnostics or prevention.

Overview

Category of Funding
Health
Funding Instruments
Cooperative Agreement
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 7/31/25 Centers for Disease Control and Prevention forecasted grant opportunity RFA-TS-26-165 for Identify and Evaluate Potential Risk Factors for Amyotrophic Lateral Sclerosis (ALS) with funding of $7.5 million. The grant will be issued under grant program 93.061 Innovations in Applied Public Health Research. It is expected that 3 total grants will be made.

Timing

Forecast Posted Date
July 31, 2025, 12:00 a.m. EDT
Est. Application Posting Date
Sept. 29, 2025, 12:00 a.m. EDT
Est. Synopsis Response Date
Dec. 1, 2025, 12:00 a.m. EST Forecasted
Last Updated
July 31, 2025, 2:13 p.m. EDT
Version
1
Archive Date
Dec. 31, 2025

Eligibility

Eligible Applicants
State governments
Native American tribal organizations (other than Federally recognized tribal governments)
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Public housing authorities/Indian housing authorities
City or township governments
Small businesses
Independent school districts
Special district governments
Native American tribal governments (Federally recognized)
Private institutions of higher education
For profit organizations other than small businesses
County governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Public and State controlled institutions of higher education
Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
Additional Info
Additional Eligibility Information to be included in the NOFO.

Award Sizing

Ceiling
$500,000
Floor
Not Listed
Estimated Program Funding
$7,500,000
Estimated Number of Grants
3

Contacts

Contact
Dr. Candis Hunter
Contact Email

Documents

Posted documents for RFA-TS-26-165

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