Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required)

Background
The National Center for Complementary and Integrative Health (NCCIH) aims to support feasibility trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) for conditions identified as high-priority research topics. These approaches are increasingly recognized as nonpharmacologic approaches to symptom management and can be complementary to conventional health care. NCCIH encourages rigorous investigation of promising mind and body interventions.

Grant Details
This funding opportunity supports feasibility clinical trials that provide new information scientifically necessary for the planning and conduct of subsequent clinical efficacy or effectiveness studies, pragmatic trials, or dissemination and implementation trials within NCCIH's mission. The subsequent full-scale clinical trial should have the potential to make a significant impact on public health. Feasibility clinical trials can fill gaps in scientific knowledge necessary to develop a competitive full-scale clinical trial, including examining feasibility and acceptability of interventions lacking published data, tailoring or adapting the content or structure of an intervention to a specific population, modality, or setting, refining the intervention to determine the most appropriate frequency or duration, determining feasibility of recruitment, retention, and data collection procedures, refining and assessing the feasibility of protocolized multi-component interventions, or examining acceptability and adherence of control conditions.

Eligibility Requirements
Eligible applicants include higher education institutions, nonprofits, for-profit organizations, state governments, county governments, city or township governments, special district governments, Indian/Native American Tribal Governments (Federally Recognized), U.S. Territory or Possession entities, independent school districts, public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), faith-based or community-based organizations, regional organizations. Foreign organizations are not eligible to apply.

Period of Performance
The maximum project period is 3 years. Applications are due by 5:00 PM local time of the applicant organization. The earliest start date is February 20, 2024.

Grant Value
This R34 grant is limited to direct costs requests of up to $450,000 over the entire project period. In no case may any year be more than $225,000 in direct costs.