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Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21)

ID: RFA-OH-26-015 • Type: Forecasted
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Description

The World Trade Center (WTC) Health Program supports exploratory and developmental research projects (R21) that address issues related to diagnostic or treatment uncertainty with respect to individuals receiving monitoring and/or treatment under subtitle C of the James Zadroga 9/11 Health and Compensation Act of 2010 as amended. This WTC Health Program R21 Notice of Funding Opportunity (NOFO) is intended to encourage exploratory/developmental research by providing support for the early and conceptual stages of project development which assess the feasibility of new areas of investigation with the potential to enhance treatment effectiveness and diagnostic practices. These studies may lead to breakthroughs in a particular area, or to the development of new interventions, techniques, agents, methodologies, models, or approaches with major clinical impacts. These studies are expected to break new ground or extend prior discoveries toward new directions or uses. Applicants are expected to propose research for which there is likely to be minimal or no preliminary data.

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Overview

Agency
Centers for Disease Control and Prevention (CDC) [HHS]
Category of Funding
Health
Funding Instruments
Grant
Grant Program (CFDA)
93.262 - Occupational Safety and Health Program
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
Grants.gov
On 10/15/25 Centers for Disease Control and Prevention forecasted grant opportunity RFA-OH-26-015 for Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21) with funding of $30.0 million. The grant will be issued under grant program 93.262 Occupational Safety and Health Program. It is expected that 60 total grants will be made.

Timing

Forecast Posted Date
Oct. 15, 2025, 12:00 a.m. EDT
Est. Application Posting Date
Dec. 5, 2025, 12:00 a.m. EST
Est. Synopsis Response Date
Feb. 12, 2026, 12:00 a.m. EST Forecasted
Last Updated
Oct. 15, 2025, 11:15 a.m. EDT
Version
1
Archive Date
Dec. 1, 2029

Eligibility

Eligible Applicants
Small businesses
Independent school districts
Native American tribal organizations (other than Federally recognized tribal governments)
City or township governments
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
State governments
For profit organizations other than small businesses
County governments
Special district governments
Public and State controlled institutions of higher education
Private institutions of higher education
Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Additional Info
Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the HHS Grants Policy Statement, are not allowed.

Award Sizing

Ceiling
$365,000
Floor
Not Listed
Estimated Program Funding
$30,000,000
Estimated Number of Grants
60

Contacts

Contact
Eduardo O'Neill, PhD, MS, MPH, Scientific Program Official
Contact Email
fzt4@cdc.gov

Documents

Posted documents for RFA-OH-26-015

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