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Evaluation of HIV Prevention and Care Interventions that Address Select Social and Structural Drivers of Inequities among Communities Disproportionately Affected by HIV

ID: CDC-RFA-PS-24-0146 • Type: Forecasted

Description

HIV surveillance data continue to document disproportionate HIV incidence and prevalence rates among sexual, gender, and racial/ethnic minority groups, including gay, bisexual and other men who have sex with men (collectively referred to as MSM), Black women, and transgender women [5-7]. Interventions designed to address these disparities have largely focused on psychosocial factors and individual HIV-related risk behaviors [2]. Yet, it has become increasingly clear these approaches are, by themselves, unlikely to be sufficient in halting the spread of HIV and reducing disparities [2,8]. They fail to adequately account for the impact and intersection of broader social and structural factors (e.g., racism, discrimination, stigma, unemployment/underemployment, housing instability, among others) [3,9]. Thus, the literature calls for upstream interventions that address larger social and structural factors that drive HIV disparities [2,3,7,8,10]. Structural interventions are programs and policies designed to reduce risk and/or facilitate behavioral change by modifying factors external to and outside of the control of individuals. 2 Structural interventions have been developed that are associated with preventing HIV infection [3,4], decreasing HIV transmission [2], and increasing engagement in and continuation of HIV care [2]. However, there is a need to further adapt, implement and evaluate such interventions in a real world, rather than a research setting, informed by input from the community [1-4,8]. The current NOFO seeks to address this need. The purpose of this NOFO is to adapt, implement and conduct rigorous evaluations of interventions that would reduce select social and structural drivers of inequities in HIV (i.e., structural racism, homelessness/housing instability and unemployment/underemployment) among disproportionately affected racial and ethnic minority persons (specifically Black, Hispanic/Latino, American Indian/Alaska Native MSM and Black women) and transgender women, preferably in Ending the HIV Epidemic (EHE) priority jurisdictions [5]. As part of the approach, community members, including priority groups, will be engaged as partners throughout the intervention design/revision, implementation, evaluation, and dissemination of findings. NOFO recipients will conduct evaluability assessments prior to intervention implementation and will develop and implement a protocol to rigorously evaluate the interventions and conduct economic evaluations. Several outcomes are expected. Short-term outcomes include, but are not limited to, increased community and priority group engagement, and high-quality evaluation protocols. Intermediate outcomes relevant to intervention and evaluation implementation include, but are not limited to, increased availability and accessibility of effective and community-driven social and structural interventions, gains in health relative to the costs of evaluated interventions, increased intervention acceptability, and decreased social determinants of health as barriers to HIV prevention and care. Intermediate HIV prevention and care outcomes are the following: community-wide increase of awareness, knowledge, attitudes, and beliefs pertaining to HIV prevention and care; and increased HIV testing, linkage to HIV care, retention in HIV care, early initiation and adherence to ART, re-engagement in HIV care, and increased PrEP screening, referral, linkage, prescription and adherence. This NOFO responds to the literature which calls for a comprehensive, equity-based approach to the HIV epidemic that would address larger social and structural factors [2,8-10]. The NOFO builds upon past and current CDC program activities, with regard to community engagement, programs/activities addressing health equity, status neutral approaches, social determinants of health, and rigorous evaluation strategies [11].

Overview

Category of Funding
Health
Funding Instruments
Cooperative Agreement
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 1/26/24 National Center for HIV, Viral Hepatitis, STD, and TB Prevention forecasted grant opportunity CDC-RFA-PS-24-0146 for Evaluation of HIV Prevention and Care Interventions that Address Select Social and Structural Drivers of Inequities among Communities Disproportionately Affected by HIV with funding of $13.5 million. The grant will be issued under grant program 93.944 Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Virus Syndrome (AIDS) Surveillance. It is expected that 6 total grants will be made.

Timing

Forecast Posted Date
Jan. 26, 2024, 12:00 a.m. EST
Est. Application Posting Date
March 4, 2024, 12:00 a.m. EST
Est. Synopsis Response Date
May 3, 2024, 12:00 a.m. EDT Forecasted
Last Updated
Jan. 26, 2024, 3:13 p.m. EST
Version
1
Archive Date
June 2, 2024

Eligibility

Eligible Applicants
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Native American tribal governments (Federally recognized)
Public housing authorities/Indian housing authorities
For profit organizations other than small businesses
County governments
Small businesses
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Public and State controlled institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Special district governments
State governments
Native American tribal organizations (other than Federally recognized tribal governments)
Private institutions of higher education
City or township governments
Additional Info
State governments or their bona fide agents (includes the District of  Columbia) Local governments or their bona fide agents            Territorial governments or their bona fide agents in the Commonwealth of   Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of            Micronesia, the Republic of the Marshall Islands, and the Republic of Palau.            State controlled institutions of higher education            American Indian or Alaska Native tribal governments (federally recognized or state-recognized)  Non-government Organizations:            American Indian or Alaska native tribally designated organizations  Other:                                                 Ministries of Health The following types of Higher Education Institutions are always encouraged to apply for CDC support as Public or Private Institutions of Higher Education: Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Alaska Native and Native Hawaiian Serving Institutions

Award Sizing

Ceiling
Not Listed
Floor
Not Listed
Estimated Program Funding
$13,500,000
Estimated Number of Grants
6

Contacts

Contact
Damian Denson
Contact Email

Documents

Posted documents for CDC-RFA-PS-24-0146

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