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Development of Models, New Approach Methodologies, and Biological Materials for Studying Human Health and Diseases (R21 Clinical Trial Not Allowed)

ID: PAR-29-002 • Type: Forecasted
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Description

This notice of funding opportunity (NOFO) encourages innovative research to develop, characterize, improve or preserve research models and model related biological materials, and to develop or improve technologies, including new approach methodologies (NAMs), for studies relevant to human health and diseases. This NOFO also seeks projects aimed at improving the identification and control of factors that could confound or interfere with the use of research models in biomedical research. The proposed project must have broad applicability to multiple NIH Institutes or Centers (ICs) to align with the NIH-wide mission of the Office of Research Infrastructure Programs (ORIP). The proposed studies must include research model(s) or NAM(s) and must explore multiple body systems or multiple categories of diseases affecting multiple body systems. Applications that develop models focused on a specific disease, a narrow area of research, or a single body system, or propose studies primarily relevant to a single NIH IC will be considered not acceptable to this NOFO.

Overview

Category of Funding
Health
Funding Instruments
Grant
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 9/16/26 the National Institutes of Health forecasted grant opportunity PAR-29-002 for Development of Models, New Approach Methodologies, and Biological Materials for Studying Human Health and Diseases (R21 Clinical Trial Not Allowed). The grant will be issued under grant program 93.351 Research Infrastructure Programs. It is expected that 15 total grants will be made worth between $190,000 and $500,000.

Timing

Forecast Posted Date
Est. Application Posting Date
Est. Synopsis Response Date
Forecasted
Last Updated
Version
1

Eligibility

Eligible Applicants
For profit organizations other than small businesses
Independent school districts
Public housing authorities/Indian housing authorities
Small businesses
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Native American tribal organizations (other than Federally recognized tribal governments)
Special district governments
City or township governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
County governments
State governments
Additional Info
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Award Sizing

Ceiling
$500,000
Floor
$190,000
Estimated Program Funding
Not Provided
Estimated Number of Grants
15

Contacts

Contact
Office of Research Infrastructure Programs (ORIP)
Contact Email

Documents

Posted documents for PAR-29-002

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