Cooperative Centers on Human Immunology (U19 Clinical Trial Optional)

Background
The Cooperative Centers on Human Immunology (CCHI) program supports mechanistic and hypothesis-testing studies to discover novel molecules, mechanisms, or regulatory pathways governing function of the human immune system in both healthy and vulnerable populations. The program also supports technology development to advance studies of the human immune system. The overarching goal of the CCHI is to provide foundational information on human immune system function to support translation of immunology research into clinical benefits.

Grant Details
The program seeks applications from interdisciplinary teams to participate in the CCHI program. It supports research on human immune system regulation and function for the discovery and characterization of new principles of human immunology for the prevention and treatment of infectious and immune-mediated diseases. The program will include support of a centralized infrastructure needed to coordinate multi-disciplinary research in human immunology; continuing recruitment of outstanding immunologists to the study of the human immune system; and promotion of public data access and the flexibility to support new research opportunities as they arise.

Eligibility Requirements
Eligible applicants include higher education institutions, nonprofits, for-profit organizations, governments, and other entities such as public housing authorities, faith-based or community-based organizations, regional organizations, and Native American tribal organizations. Foreign institutions are not eligible to apply.

Period of Performance
The period of performance for the grant is expected to be up to five years.

Grant Value
$13.7 million in FY2024 is intended to fund 4-5 awards with direct costs not expected to exceed $2.5 million per year.