Clinical Sites for the Environmental influences on Child Health Outcomes (ECHO) IDeA States Pediatric Clinical Trials Network - 3 (UG1 Clinical Trial Required)

Background
This Notice of Funding opportunity (NOFO), issued by the Office of the Director (OD), National Institutes of Health (NIH), invites applications from entities/institutions in Institutional Development Award (IDeA)-eligible States to participate as Clinical Sites in the Environmental influences on Child Health Outcomes IDeA States Pediatric Clinical Trials Network (ECHO ISPCTN). The ECHO ISPCTN is the intervention component of the ECHO program and supports its overall mission to enhance the health of children for generations to come.

The ECHO ISPCTN aims to provide valid and generalizable answers to intervention research questions relevant to the health of children from rural or underserved backgrounds.

Grant Details
Each ISPCTN Clinical Site will support site readiness to participate in approximately five ECHO ISPCTN multicenter pediatric clinical trials related to prevention or treatment of one or more of ECHOs five outcome areas of interest: pre-, peri-, and postnatal outcomes; upper and lower airways; obesity; neurodevelopment; and positive health. The Clinical Site will have responsibility to develop, conduct, and disseminate findings from multicenter clinical trials research, assuring the participation of children living in rural or underserved communities in IDeA states, build pediatric clinical trial research capacity in IDeA states funded by the ECHO ISPCTN, and engage interested parties such as community members, nonprofit organizations, and professional societies to enhance ECHO ISPCTN clinical trial impact, transferability, rigor, and feasibility.

Eligibility Requirements
Only institutions or organizations in the following IDeA states/commonwealth are eligible to respond to this NOFO: Alaska, Arkansas, Delaware, Hawaii, Idaho, Kansas, Kentucky, Louisiana, Maine, Mississippi, Montana, Nebraska, Nevada, New Hampshire, New Mexico, North Dakota, Oklahoma, Puerto Rico, Rhode Island, South Carolina, South Dakota,Vermont West Virginia,and Wyoming.

Period of Performance
The period of performance for this grant is 5 years.

Grant Value
NIH intends to fund an estimate of 15-20 awards for a total of $7,000,000 for fiscal year 2025. Applicants may request direct cost budgets of up to $300,000 for each of the five years of the award.