Changing Health Systems Using Evidence-based interventions to increase Colorectal Cancer Screening

Background
The Centers for Disease Control and Prevention (CDC) is issuing this funding opportunity to address the low prevalence of colorectal cancer (CRC) screening among populations aged 45 to 75 years. The goal is to increase screening rates through evidence-based interventions (EBIs) in partnership with health systems and primary care clinics, particularly those serving populations with lower screening prevalence and barriers to access. This initiative aims to prevent CRC through early detection and removal of polyps, thereby reducing mortality rates associated with the disease.

Grant Details
Recipients will partner with health systems and primary care clinics that have a CRC screening prevalence below national, regional, or local averages. They will implement at least three multicomponent EBIs recommended in The Community Guide, focusing on increasing demand, access, and delivery of screening recommendations. Key tasks include:

- Establishing partnerships with clinics;
- Conducting readiness assessments;
- Ensuring clinics have a CRC screening champion;
- Utilizing limited funding for stool-based testing and follow-up colonoscopies;
- Submitting high-quality clinic-level data on screening prevalence;
- Tracking the entire CRC screening process;
- Submitting success stories every six months; and
- Planning an annual evaluation report.

Eligibility Requirements
Eligible applicants include state governments, county governments, city or township governments, special district governments, independent school districts, public and state-controlled institutions of higher education, Federally Qualified Health Centers (FQHCs), community health centers, Native American tribal governments (federally recognized), urban Indian organizations, public housing authorities, nonprofit organizations (both with and without 501(c)(3) status), private institutions of higher education, for-profit organizations other than small businesses, and small businesses.

Period of Performance
The expected period of performance spans five years with projects awarded for five 12-month budget periods.

Grant Value
The total program funding over the performance period is expected to be $110 million. Each budget period may receive up to $22 million in total funding. Individual grant awards will range from $350,000 to $900,000 per applicant per budget period, with an expected average award amount of $500,000.

Place of Performance
The grant activities are expected to be performed in various states across the U.S., specifically targeting areas with low CRC screening prevalence.