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Ceres

ID: HR001123S0012 • Type: Posted

Description

Conventional soil bioremediation is laborious, inefficient, and expensive, requiring soil preparation, nutrient delivery to remediating organisms, and continuous site monitoring. Plants and their rhizosphere microbiomes have innate potential to inexpensively perform the costliest aspects of bioremediation soil preparation, nutrient augmentation, and site monitoring without routine human intervention. Leveraging the inherent plant-rhizosphere community, Ceres will enhance community performance by engineering synthetic communities to achieve autonomous bioremediation of a fuel, JP-8, and an explosive, TNT, from soil while overtly reporting the status of this remediation. Advances in both synthetic biology and synthetic ecology will be used to create and optimize these sophisticated synthetic communities.
Background
The Defense Advanced Research Projects Agency (DARPA), Biological Technologies Office (BTO) is soliciting proposals for the Ceres project. The project aims to develop innovative technologies and approaches to build synthetic plant-microbe communities for autonomous bioremediation of fuel, JP-8, and explosive TNT from soil while overtly reporting the status of this remediation. The project seeks to reduce the cost of remediation by leveraging natural behaviors and processes performed by plant-microbe communities.

Grant Details
The project will be divided into two 24-month phases and one 6-month phase comprised of a final demonstration performed by an independent verification and validation (IV&V) team. The Cleaner Track will focus on developing synthetic plant-rhizosphere microbial communities that would degrade the targeted contaminant down to EPA-approved levels without dangerous byproducts. The Beacon Track will develop a complementary plant-microbe synthetic community that would provide an overt signal that the target contamination has been reduced to EPA-approved levels. Proposers may choose a Combined Track to address both Cleaner and Beacon for TNT or JP-8.

Eligibility Requirements
The BAA is open to eligible applicants, and proposers must address all four technical areas: Engineer Root Communities, Engineer Plants, Engineer Ecological Containment, and Develop Testbeds. Proposals must also propose additional quantitative and qualitative success criteria as needed.

Period of Performance
The project spans 4.5 years, with Phase I lasting 24 months, an optional Phase II lasting 24 months, and a final IV&V 6-month demonstration in Phase III. Progress towards the program goal will be determined through regular milestones, metrics, and deliverables.

Grant Value
The total value of the grant is not specified in the provided document.

Overview

Category of Funding
Science and Technology and other Research and Development
Funding Instruments
Cooperative Agreement
Other
Procurement Contract
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 10/13/22 Defense Advanced Research Projects Agency posted grant opportunity HR001123S0012 for Ceres. The grant will be issued under grant program 12.910 Research and Technology Development.

Timing

Posted Date
Oct. 13, 2022, 12:00 a.m. EDT
Closing Date
Jan. 11, 2023, 12:00 a.m. EST Past Due
Closing Date Explanation
See Full Announcement for details.
Last Updated
Nov. 8, 2022, 8:35 a.m. EST
Version
2
Archive Date
Feb. 10, 2023

Eligibility

Eligible Applicants
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Info
All responsible sources capable of satisfying the Government's needs may submit a proposal that shall be considered by DARPA. See the Eligibility Information section of the BAA for more information.

Contacts

Contact
DARPA - Biological Technologies Office
Contact Email
Email Description
None
Contact Phone
(571) 218-4963
Additional Information
SAM.gov Contract Opportunities

Documents

Posted documents for HR001123S0012

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