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BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs - eTeamBCP (U01 Clinical Trials Optional)

ID: RFA-NS-23-025 • Type: Posted
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Description

Reissue of RFA-NS-22-028 to comply with DMSP - No new dates are being added. Reissue of:RFA-NS-18-029 and RFA-NS-20-029. This funding opportunity announcement (FOA) is designed to support teams of investigators that seek to cross boundaries of interdisciplinary collaboration to elucidate the contributions of dynamic circuit activity to a specific behavioral or neural system. Applications are encouraged to propose adventurous and challenging goals that can only be tackled by a synergistic team-based approach and have the potential to be transformative and/or to enable significant advances. These studies at the exploratory stage are intended for the development of experimental capabilities and/or theoretical frameworks in preparation for a future competition for larger-scale or extended efforts, including the BRAIN TargetedBCP R01 or the multi-component, Team-Research BRAIN Circuit Programs (U19).The overall goal of this FOA is to enable a large-scale analysis of neural systems and circuits within the context and during the simultaneous measurement of an ethologically relevant behavior. Toward this end, teams are expected to assemble and leverage multi-disciplinary expertise, and to integrate experimental with computational and theoretical approaches. Teams are expected to bridge fields by incorporating rich information on cell-types, on circuit functionality and connectivity, in conjunction with sophisticated analyses of an ethologically relevant behavior of an organism or a well-defined neural system. Teams are also expected to aim for a mechanistic understanding of the circuits of the central nervous system (CNS) by applying cutting-edge methods such as those for large-scale recording, manipulation, and analysis of neural circuits across multiple regions of the CNS.

Background
The BRAIN Initiative, initiated in 2014, aims to accelerate the development and application of innovative neurotechnologies to understand the brain's dynamic activity and its potential for treating and preventing brain disorders. The initiative is guided by strategic plans such as 'BRAIN 2025: A Scientific Vision' and 'The BRAIN Initiative 2.0: From Cells to Circuits, Toward Cures'. It encourages inclusivity in research, transdisciplinary collaborations, and engagement from diverse scientific workforce.

Grant Details
This funding opportunity supports teams of three or more investigators seeking to elucidate the contributions of dynamic circuit activity to a specific behavioral or neural system. The goal is to enable a large-scale analysis of neural systems and circuits within the context of an ethologically relevant behavior. Teams are expected to integrate experimental with computational and theoretical approaches, bridge fields, and aim for a mechanistic understanding of the circuits of the central nervous system (CNS) using cutting-edge methods for recording, manipulation, and analysis of neural circuits across multiple regions of the CNS.

Eligibility Requirements
Eligible applicants include higher education institutions, nonprofits, for-profit organizations, state and local governments, federal agencies, U.S. territories or possessions, and others. Foreign institutions are not eligible to apply directly but can participate as foreign components. Individuals with the necessary skills and resources are invited to apply as Program Directors/Principal Investigators (PDs/PIs). The application must be submitted as a multiple PD/PI application with 3-6 PDs/PIs.

Period of Performance
The project period must be three years. The open date for submission is May 15, 2023, with an earliest start date of June 15, 2023. The expiration date for this opportunity is May 7, 2024.

Grant Value
The NIH BRAIN Initiative intends to commit up to $12M per fiscal year to fund around 5 awards under this opportunity.
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Overview

Agency
National Institutes of Health (NIH) [HHS]
Category of Funding
Education
Health
Income Security and Social Services
Funding Instruments
Cooperative Agreement
Grant Program (CFDA)
93.173 - Research Related to Deafness and Communication Disorders
93.213 - Research and Training in Complementary and Integrative Health
93.242 - Mental Health Research Grants
93.273 - Alcohol Research Programs
93.279 - Drug Abuse and Addiction Research Programs
93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health
93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders
93.865 - Child Health and Human Development Extramural Research
93.866 - Aging Research
93.867 - Vision Research
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
Grants.gov
On 4/25/23 the National Institutes of Health posted grant opportunity RFA-NS-23-025 for BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs - eTeamBCP (U01 Clinical Trials Optional). The grant will be issued under grant program 93.173 Research Related to Deafness and Communication Disorders.

Timing

Posted Date
April 25, 2023, 12:00 a.m. EDT
Closing Date
May 7, 2024, 12:00 a.m. EDT Past Due
Last Updated
May 7, 2024, 11:52 a.m. EDT
Version
2
Archive Date
June 6, 2024

Eligibility

Eligible Applicants
Public housing authorities/Indian housing authorities
Independent school districts
For profit organizations other than small businesses
State governments
Private institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Special district governments
Native American tribal governments (Federally recognized)
County governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Public and State controlled institutions of higher education
Small businesses
City or township governments
Additional Info
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Contacts

Contact
National Institutes of Health
Contact Email
grantsinfo@nih.gov
Email Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Contact Phone
(301) 402-2541
Additional Information
https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-23-025.html
Additional Information Site
http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-23-025.html

Documents

Posted documents for RFA-NS-23-025

Grant Awards

Grants awarded through RFA-NS-23-025

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