Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed)

Background
The National Institutes of Health (NIH), through the Office of Research Infrastructure Programs (ORIP), is issuing this Notice of Funding Opportunity (NOFO) to support Animal and Biological Material Resource Centers. These Centers aim to provide essential resources for the biomedical research community, including specialized colonies of laboratory animals, informatics tools, reagents, and genetic stocks.

The goal is to enhance scientific rigor, transparency, and reproducibility in biomedical research across various NIH Institutes and Centers.

Grant Details
The funding opportunity supports the creation, collection, development, characterization, preservation, and distribution of special colonies of laboratory animals and associated resources. Key tasks include:
1) Providing high-quality animal models that are not generally available;
2) Offering informatics tools and analytical expertise;
3) Ensuring broad applicability across multiple NIH ICs;
4) Coordinating with efforts to develop new approach methodologies (NAMs) that complement traditional animal-based research;
5) Conducting applied research to generate comparative data that enhances the applicability of NAMs;
6) Maintaining a Curation and Informatics component for data management;
7) Developing a disaster preparedness plan for resource preservation;
8) Establishing an External Advisory Board for oversight and guidance.

Eligibility Requirements
Eligible applicants include higher education institutions, nonprofits, for-profit organizations, local governments, state governments, and federal agencies. Non-domestic entities are not eligible to apply. Applicants must demonstrate institutional commitment and provide evidence of support from the scientific community.

Period of Performance
The maximum project period is five years. The earliest start date for awarded projects is February 18, 2026.

Grant Value
NIH intends to commit $1.3 million in FY 2023-2025 to fund at least two awards per fiscal year. Application budgets are not limited but must reflect the actual needs of the proposed project.

Place of Performance
The grant activities will be performed at institutions that meet eligibility requirements across the United States.