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Age-related Macular Degeneration (AMD) Integrative Biology Initiative: Discovery of AMD Pathobiology using Patient-Derived Induced Pluripotent Stem Cell (iPSC)-derived Retinal Pigment Epithelium (RPE) (U01 Clinical Trial Not Allowed)

ID: RFA-EY-21-002 • Type: Posted
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Description

Posted: Nov. 17, 2021, 12:00 a.m. EST
This Funding Opportunity Announcement (FOA) aims to support collaborative studies of a unique resource of patient-derived induced pluripotent stem cell (iPSC) lines generated by the NEI age-related macular degeneration (AMD) Integrative Biology Initiative. This resource also includes clinical, genomic, and imaging data from the patients from which these cells were derived, and a set of isogenic control cell lines in which the risk allele(s) have been corrected. These cell lines and clinical data are from patients with AMD carrying high prevalence risk alleles selected from the Age-Related Eye Disease Study 2 (AREDS2). The goal of this FOA is to determine if these iPSC-derived cell lines can be used to discover the underlying pathophysiology of AMD. Collaborative effort is highly encouraged with investigators bringing in the needed areas of expertise for successful projects.
Posted: Dec. 1, 2020, 12:00 a.m. EST
Posted: Dec. 1, 2020, 12:00 a.m. EST

Overview

Category of Funding
Health
Funding Instruments
Cooperative Agreement
Grant Program (CFDA)
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
On 11/17/21 the National Institutes of Health posted grant opportunity RFA-EY-21-002 for Age-related Macular Degeneration (AMD) Integrative Biology Initiative: Discovery of AMD Pathobiology using Patient-Derived Induced Pluripotent Stem Cell (iPSC)-derived Retinal Pigment Epithelium (RPE) (U01 Clinical Trial Not Allowed). The grant will be issued under grant program 93.867 Vision Research.

Timing

Posted Date
Nov. 17, 2021, 12:00 a.m. EST
Closing Date
Feb. 17, 2022, 12:00 a.m. EST Past Due
Last Updated
Nov. 17, 2021, 11:16 a.m. EST
Version
1
Archive Date
March 25, 2022

Eligibility

Eligible Applicants
Public housing authorities/Indian housing authorities
County governments
City or township governments
Native American tribal governments (Federally recognized)
Native American tribal organizations (other than Federally recognized tribal governments)
State governments
For profit organizations other than small businesses
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Special district governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Small businesses
Independent school districts
Public and State controlled institutions of higher education
Private institutions of higher education
Additional Info
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Award Sizing

Ceiling
$250,000
Floor
Not Listed
Estimated Program Funding
Not Provided
Estimated Number of Grants
Not Listed

Contacts

Contact
National Institutes of Health
Email Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Contact Phone
(301) 402-2541

Documents

Posted documents for RFA-EY-21-002

Grant Awards

Grants awarded through RFA-EY-21-002

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