Accelerating Lesotho's Progress to Epidemic Control Through Health System Strengthening and Delivery of Comprehensive HIV/TB Care, Treatment and Prevention Services under the President's Emergency Plan for AIDS Relief (PEPFAR)

The Award Ceiling for Year 1 is 0 (none). CDC anticipates an Approximate Total Fiscal Year Funding amount of $16,000,000 for Year 1, subject to the availability of funds. Lesotho has a generalized HIV epidemic with prevalence of 25.6% among persons aged 15-59. The annual HIV incidence is among the highest in the world at 1.1% among adults 15-59. Lesotho has a high TB burden with an estimated incidence of 15,000 TB cases per annum. This NOFO aims to maximize impact through continued scale-up of comprehensive HIV and TB prevention, care, and treatment services in Lesotho, focusing on preventing new HIV infections, reducing HIV-related morbidity and mortality, and strengthening systems for sustainable HIV and TB control service delivery for all populations in Lesotho. The NOFO is aligned with the national HIV and TB implementation plans. The overall aim is to assist the Government of Lesotho (GOL) in reaching and sustaining HIV epidemic control. This NOFO will support provision of scalable, high quality, comprehensive, evidence-based HIV prevention, care, and treatment services including expanded HIV case identification and same-day linkage to antiretroviral therapy (ART), prevention of mother to child transmission (PMTCT), and TB prevention, diagnosis, and management. A major strategy of the NOFO is strengthening Ministry of Health (MOH) capacity to implement and manage HIV/TB programs in supported facilities. It is expected that this approach will help to identify system barriers and bottlenecks affecting efforts to reach the 95-95-95 goals.