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​Sickle Cell Disease Regional Care Excellence (SoRCE) Program

ID: HRSA-26-052 • Type: Forecasted
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Description

Sickle Cell Disease Regional Care Excellence Program (SoRCE) is to improve the health of people with sickle cell disease (SCD) by expanding access to care, improving the quality of care, and tracking quality of life indicators. There are approximately 100,000 people in the United States with SCD. Treatment starting in early childhood can prevent or reduce complications such as severe pain episodes, silent strokes, and premature death. Despite universal identification at birth, fewer than half of children with SCD receive needed treatment. As these children become adolescents and transition to adulthood many are not appropriately identified as candidates for disease-modifying therapies, in part because their doctors are still learning how to use the latest treatments. The program is made up of seven regions with one award recipient per region serving as a Regional Coordinating Hub (RCH). Each award recipient will work with clinical and community-based partners in their region and engage in continuous quality improvement (CQI) initiatives to improve access and quality of care.

Background
The Sickle Cell Disease Regional Care Excellence Program (SoRCE) aims to improve the health of individuals with sickle cell disease (SCD) by enhancing access to care, improving care quality, and monitoring quality of life indicators. Approximately 100,000 people in the United States are affected by SCD. Early treatment can prevent severe complications; yet less than half of children diagnosed with SCD receive necessary treatment. The program consists of seven regions, each with one award recipient designated as a Regional Coordinating Hub (RCH). These hubs will collaborate with clinical and community partners to implement continuous quality improvement initiatives.

Grant Details
The grant involves tasks such as expanding access to care for individuals with sickle cell disease, improving the quality of care provided, and tracking indicators related to quality of life. Award recipients will engage in continuous quality improvement initiatives and work closely with both clinical and community-based partners in their respective regions.

Eligibility Requirements
Eligibility is likely limited to organizations that can effectively serve as Regional Coordinating Hubs and demonstrate capability in improving healthcare access and quality for sickle cell disease patients.

Grant Value
The total value of the grant opportunity is not specified. Individual grant awards may vary based on regional needs and proposals submitted by applicants.

Place of Performance
The grant will be performed across seven designated regions within the United States.
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Overview

Agency
Health Resources and Services Administration (HRSA) [HHS]
Category of Funding
Health
Funding Instruments
Cooperative Agreement
Grant Program (CFDA)
93.365 - Sickle Cell Treatment Demonstration Program
Grant Category
Discretionary
Cost Sharing / Matching Requirement
False
Source
Grants.gov
On 12/11/25 Health Resources and Services Administration forecasted grant opportunity HRSA-26-052 for ​Sickle Cell Disease Regional Care Excellence (SoRCE) Program with funding of $6.7 million. The grant will be issued under grant program 93.365 Sickle Cell Treatment Demonstration Program. It is expected that 7 total grants will be made.

Timing

Forecast Posted Date
Dec. 11, 2025, 12:00 a.m. EST
Est. Application Posting Date
April 1, 2026, 12:00 a.m. EDT
Est. Synopsis Response Date
May 31, 2026, 12:00 a.m. EDT Forecasted
Last Updated
Dec. 11, 2025, 4:20 p.m. EST
Version
1
Archive Date
June 30, 2026

Eligibility

Eligible Applicants
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Public and State controlled institutions of higher education
Private institutions of higher education
Additional Info
Hospitals or clinicsHealth centers.Documentation must be provided to demonstrate that your organization has at least five years of experience in working with individuals who have sickle cell disease (SCD).​

Award Sizing

Ceiling
$950,000
Floor
Not Listed
Estimated Program Funding
$6,650,000
Estimated Number of Grants
7

Contacts

Contact
MCHB
Contact Email
scdprograms@hrsa.gov

Documents

Posted documents for HRSA-26-052

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